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Table 3 Comparisons of parameters of CRRT among the study groups after connecting additional pressure control lines

From: Using additional pressure control lines when connecting a continuous renal replacement therapy device to an extracorporeal membrane oxygenation circuit

CRRT parameters

No line group

(n = 16)

Single line group

(n = 36)

Double line group

(n = 118)

P value

Pressures on CRRT circuit

 Access pressure, mmHg

163 (117–185)

−37 (−65–57)

2 (−42–52)

< 0.001*†

 Filter pressure, mmHg

−17(−67–24)

−25 (−49–25)

119 (73–167)

< 0.001†‡

 Effluent pressure, mmHg

−101 (−138 – −24)

−104 (−139 – −59)

19 (−17–60)

< 0.001†‡

 Return pressure, mmHg

−81 (−108 – −41)

−71 (−108 – −44)

68 (29–107)

< 0.001†‡

 Transmembrane pressure, mmHg

57 (36–93)

53 (25–78)

58 (46–69)

0.746

 Pressure drop, mmHg

36 (28–42)

32 (20–42)

25 (16–33)

0.003

Change in laboratory findings

 ∆PLT between H0 and H24, mg/dL

−27 (−68 – −3)

−1 (−51–27)

−15 (−41–7)

0.289

 ∆PLT between H0 and H48, mg/dL

−41 (−101–4)

4 (−76–13)

−16 (−45–12)

0.427

 ∆LD between H0 and H24, IU/L

482 (−650–3405)

384 (−109–1580)

−3 (−237–248)

0.069

 ∆LD between H0 and H48, IU/L

482 (−53–2648)

−22 (−2237–1237)

−20 (−496–263)

0.354

 ∆pHb between H0 and H24 (n = 17), mg/dL

NA

23.5 (9 – NA)

−5 (−20–2)

0.037

 ∆pHb between H0 and H48 (n = 23), mg/dL

NA

12.5 (12 – NA)

3 (−5–8)

0.100

Lifespan of CRRT circuit, hours

21.8 (11.6–31.8)

23.0 (15.0–34.6)

45.0 (29.0–63.7)

< 0.001†‡

  1. CRRT continuous renal replacement therapy, LD lactate dehydrogenase, pHb plasma hemoglobin, PLT platelets
  2. Superscripts *, †, ‡ indicate significant differences (p < 0.05) between the no line group and the single line group, the no line group and the double line group, and the single line group and the double line group, respectively