Table 2 Results from multivariable Model 2 (adjusted for caffeine) for ln(htTKV) and for mGFR

Age

0.017

0.010, 0.025

<  0.001

−1.362

− 1.700, − 1.024

<  0.001

Sex (Male)

0.084

− 0.040, 0.208

0.195

−0.990

−6.757, 4.780

0.741

Race (White)

0.083

−0.101, 0.268

0.386

−0.811

−9.529, 7.880

0.858

BMI

0.006

−0.006, 0.018

0.345

−0.454

−1.001, 0.094

0.112

Smoke (Yes)

0.072

−0.091, 0.236

0.393

3.474

−4.111, 11.053

0.378

Hypertension (Yes)

0.395

0.263, 0.527

<  0.001

−11.946

−18.060, −5.821

<  0.001

Gene type

<  0.001*

0.018*

PKD1 + truncation

Reference

–

Reference

–

PKD1 + no truncation

− 0.082

− 0.227, 0.064

1.475

− 5.263, 8.208

PKD2 + NMD

−0.504

− 0.664, − 0.344

10.840

3.427, 18.237

Caffeine (Any)

−0.146

−0.295, 0.003

0.061

1.395

−5.908, 8.714

0.713

Caffeine:Time (Any)

0.006

0.002, 0.011

0.007

0.069

−0.495, 0.631

0.811

Time

0.045

0.041, 0.049

<  0.001

−2.696

−3.187, −2.200

<  0.001

Random Effect

Variance

Standard Deviation

Variance

Standard Deviation

Patient

0.224

0.474

425.0

20.62

Residual

0.016

0.127

372.8

19.31