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Table 4 Detection of AKI using Cys C by quintiles of FT3

From: Impact of thyroid function on cystatin C in detecting acute kidney injury: a prospective, observational study

 

Total AKIa

Established AKIb

Later-onset AKIc

AUC ROC

95%CI

Cut-off

P

AUC ROC

95%CI

Cut-off

P

AUC ROC

95%CI

Cut-off

P

Total

0.753 ± 0.015

0.724–0.782

1.03

< 0.001

0.797 ± 0.017

0.763–0.831

0.98

< 0.001

0.669 ± 0.022

0.626–0.712

1.03

< 0.001

I (n = 268)

0.777 ± 0.028

0.722–0.832

1.24

< 0.001

0.786 ± 0.030

0.727–0.845

1.22

< 0.001

0.667 ± 0.050

0.570–0.764

1.21

0.001

II (n = 268)

0.740 ± 0.035

0.671–0.809

0.98

< 0.001

0.799 ± 0.045

0.712–0.887

1.10

< 0.001

0.658 ± 0.048

0.564–0.751

0.71

0.003

III (n = 267)

0.721 ± 0.037

0.648–0.793

0.99

< 0.001

0.774 ± 0.042

0.691–0.857

0.90

< 0.001

0.617 ± 0.057

0.505–0.729

1.04

0.049

IV (n = 268)

0.727 ± 0.035

0.658–0.795

0.78

< 0.001

0.751 ± 0.049

0.655–0.846

0.82

< 0.001

0.694 ± 0.044

0.608–0.780

0.60

< 0.001

V (n = 268)

0.700 ± 0.039

0.624–0.776

0.79

< 0.001

0.733 ± 0.049

0.637–0.829

0.79

0.001

0.661 ± 0.052

0.559–0.762

1.03

0.003

  1. aFor Total AKI, Quintile I versus Quintile II Z = 0.825, P = 0.409; Quintile I versus Quintile III Z = 1.207, P = 0.227; Quintile I versus Quintile IV Z = 1.116, P = 0.265; Quintile I versus Quintile V Z = 1.604, P = 0.109; Quintile II versus Quintile III Z = 0.373, P = 0.709; Quintile II versus Quintile IV Z = 0.263, P = 0.793; Quintile II versus Quintile V Z = 0.763, P = 0.445; Quintile III versus Quintile IV Z = 0.118, P = 0.906; Quintile III versus Quintile V Z = 0.391, P = 0.696; Quintile IV versus Quintile V Z = 0.515, P = 0.606. bFor Established AKI, Quintile I versus Quintile II Z = 0.240, P = 0.810; Quintile I versus Quintile III Z = 0.232, P = 0.816; Quintile I versus Quintile IV Z = 0.609, P = 0.542; Quintile I versus Quintile V Z = 0.922, P = 0.356; Quintile II versus Quintile III Z = 0.406, P = 0.685; Quintile II versus Quintile IV Z = 0.721, P = 0.471; Quintile II versus Quintile V Z = 0.992, P = 0.321; Quintile III versus Quintile IV Z = 0.356, P = 0.721; Quintile III versus Quintile V Z = 0.635, P = 0.525; Quintile IV versus Quintile V Z = 0.260, P = 0.795. cFor Later-onset AKI, Quintile I versus Quintile II Z = 0.130, P = 0.897; Quintile I versus Quintile III Z = 0.660, P = 0.510; Quintile I versus Quintile IV Z = 0.405, P = 0.685; Quintile I versus Quintile V Z = 0.083, P = 0.934; Quintile II versus Quintile III Z = 0.550, P = 0.582; Quintile II versus Quintile IV Z = 0.553, P = 0.580; Quintile II versus Quintile V Z = 0.042, P = 0.966; Quintile III versus Quintile IV Z = 1.069, P = 0.285; Quintile III versus Quintile V Z = 0.570, P = 0.568; Quintile IV versus Quintile V Z = 0.484, P = 0.628. AKI acute kidney injury, AUC ROC area under the receiver operating characteristic curve, CI confidence interval, Cys C cystatin C, FT3 free triiodothyronine
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BMC Nephrology

ISSN: 1471-2369

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