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Table 5 Detection of AKI using Cys C by quintiles of TT3

From: Impact of thyroid function on cystatin C in detecting acute kidney injury: a prospective, observational study

 

Total AKIa

Established AKIb

Later-onset AKIc

AUC ROC

95%CI

Cut-off

P

AUC ROC

95%CI

Cut-off

P

AUC ROC

95%CI

Cut-off

P

Total

0.753 ± 0.015

0.724–0.782

1.03

< 0.001

0.797 ± 0.017

0.763–0.831

0.98

< 0.001

0.669 ± 0.022

0.626–0.712

1.03

< 0.001

I (n = 268)

0.784 ± 0.028

0.729–0.838

1.22

< 0.001

0.804 ± 0.029

0.747–0.861

1.09

< 0.001

0.651 ± 0.051

0.551–0.751

1.26

0.003

II (n = 268)

0.738 ± 0.033

0.672–0.803

1.03

< 0.001

0.781 ± 0.039

0.705–0.856

0.98

< 0.001

0.652 ± 0.049

0.555–0.748

1.03

0.004

III (n = 268)

0.730 ± 0.035

0.661–0.799

1.07

< 0.001

0.786 ± 0.044

0.699–0.873

0.89

< 0.001

0.657 ± 0.048

0.562–0.752

1.03

0.003

IV (n = 268)

0.708 ± 0.040

0.629–0.786

0.99

< 0.001

0.706 ± 0.055

0.597–0.814

0.93

< 0.001

0.690 ± 0.054

0.585–0.795

0.68

0.002

V (n = 267)

0.707 ± 0.038

0.633–0.781

0.79

< 0.001

0.757 ± 0.050

0.660–0.855

0.81

< 0.001

0.670 ± 0.046

0.579–0.761

0.79

0.001

  1. aFor Total AKI, Quintile I versus Quintile II Z = 1.063, P = 0.288; Quintile I versus Quintile III Z = 1.205, P = 0.228; Quintile I versus Quintile IV Z = 1.557, P = 0.120; Quintile I versus Quintile V Z = 1.631, P = 0.103; Quintile II versus Quintile III Z = 0.166 P = 0.868; Quintile II versus Quintile IV Z = 0.579,P = 0.563; Quintile II versus Quintile V Z = 0.616, P = 0.538; Quintile III versus Quintile IV Z = 0.414, P = 0.679; Quintile III versus Quintile V Z = 0.445, P = 0.656; Quintile IV versus Quintile V Z = 0.018, P = 0.986. bFor Established AKI, Quintile I versus Quintile II Z = 0.473, P = 0.636; Quintile I versus Quintile III Z = 0.342, P = 0.733; Quintile I versus Quintile IV Z = 1.576, P = 0.115; Quintile I versus Quintile V Z = 0.813, P = 0.416; Quintile II versus Quintile III Z = 0.085, P = 0.932; Quintile II versus Quintile IV Z = 1.112, P = 0.266; Quintile II versus Quintile V Z = 0.378, P = 0.705; Quintile III versus Quintile IV Z = 1.136, P = 0.256; Quintile III versus Quintile V Z = 0.435, P = 0.663; Quintile IV versus Quintile V Z = 0.686, P = 0.493. cFor Later-onset AKI, Quintile I versus Quintile II Z = 0.014, P = 0.989; Quintile I versus Quintile III Z = 0.086, P = 0.931; Quintile I versus Quintile IV Z = 0.525, P = 0.600; Quintile I versus Quintile V Z = 0.277, P = 0.782; Quintile II versus Quintile III Z = 0.073, P = 0.942; Quintile II versus Quintile IV Z = 0.521, P = 0.602; Quintile II versus Quintile V Z = 0.268, P = 0.789; Quintile III versus Quintile IV Z = 0.457, P = 0.648; Quintile III versus Quintile V Z = 0.196, P = 0.845; Quintile V versus Quintile IV Z = 0.282, P = 0.778. AKI acute kidney injury, AUC ROC area under the receiver operating characteristic curve, CI confidence interval, Cys C cystatin C, TT3 total triiodothyronine
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BMC Nephrology

ISSN: 1471-2369

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