Variable | Classifications of baseline 25(OH)D level | Quintiles of baseline 25(OH)D level | Total | ||||||
---|---|---|---|---|---|---|---|---|---|
< 50 nmol/L | 50–75 nmol/L | ≥75 nmol/L | ≤30 nmol/L | 30–40 nmol/L | 40–50 nmol/L | 50-63 nmol/L | >63 nmol/L | ||
Albuminuria | |||||||||
Number of incident cases | 109 | 10 | 3 | 53 | 35 | 21 | 7 | 6 | 122 |
Incidence (%) | 17.6 (14.6–20.6) | 3.2 (1.2–5.1) | 2.9 (0.3–5.6) | 25.6 (19.7–31.6) | 16.2 (11.3–21.1) | 10.8 (6.4–15.1) | 3.6 (1.0–6.2) | 2.7 (0.6–4.8) | 11.8 (9.8–13.7) |
Total person-years | 1895 | 1012 | 328 | 632 | 661 | 605 | 622 | 715 | 3253 |
Incidence rate (per 100 person years) | 5.8 (4.8–6.9) | 1.0 (0.6–1.8) | 0.9 (0.3–2.8) | 8.4 (6.4–11.0) | 5.3 (3.8–7.4) | 3.5 (2.3–5.3) | 1.1 (0.5–2.4) | 0.8 (0.4–1.8) | 3.8 (3.1–4.5) |
Impaired eGFR | |||||||||
Number of incident cases | 117 | 36 | 6 | 48 | 41 | 28 | 24 | 18 | 159 |
Incidence (%) | 18.9 (15.8–22.0) | 11.4 (7.9–14.8) | 5.9 (1.3–10.4) | 23.2 (17.4–28.9) | 19.0 (13.8–24.2) | 14.4 (9.4–19.3) | 12.2 (7.9–15.3) | 8.1 (4.5–11.6) | 15.3 (13.1–17.5) |
Total person-years | 1884 | 975 | 322 | 639 | 651 | 593 | 600 | 698 | 3181 |
Incidence rate (per 100 person years) | 6.2 (5.2–7.4) | 3.7 (2.7–5.2) | 1.9 (0.8–4.1) | 7.5 (5.7–9.7) | 6.3 (4.6–8.6) | 47 (3.3–6.8) | 4.0 (2.7–6.0) | 2.6 (1.6–4.1) | 5.0 (4.3–5.8) |
CKD | |||||||||
Number of incident cases | 202 | 45 | 8 | 92 | 66 | 44 | 30 | 23 | 255 |
Incidence (%) | 32.7 (29.0–36.4) | 14.2 (10.4–18.0) | 7.8 (2.6–13.1) | 44.4 (37.7–51.2) | 30.6 (24.4–36.7) | 22.6 (16.7–28.4) | 15.3 (10.3–20.3) | 10.3 (6.3–14.3) | 24.6 (22.0–27.2) |
Total person-years | 1850 | 967 | 318 | 621 | 645 | 585 | 596 | 689 | 3135 |
Incidence rate (per 100 person years) | 10.9 (9.5–12.5) | 4.7 (3.5–6.2) | 2.5 (1.3–5.0) | 14.8 (12.1–18.2) | 10.2 (8.0–13.0) | 7.5 (5.6–10.1) | 5.0 (3.5–7.2) | 3.3 (2.0–5.0) | 8.1 (7.2–9.2) |