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Table 1 Baseline Biochemical Characteristics of Patients Receiving Garlic powder or Placebo

From: Evaluating the effect of garlic extract on serum inflammatory markers of peritoneal dialysis patients: a randomized double-blind clinical trial study

Variable

Control group (N = 21)

Garlic group (N = 19)

P-value

 

Age (Year)

52.8 ± 18.8

56.0 ± 16.1

0.56a

BMI (Kg/m2)

25.9 ± 4.5

26.3 ± 5.4

0.80a

Peritoneal dialysis duration (month)

30.7 ± 3.2

33.1 ± 2.8

0.47a

Gender

Male

9 (42.8)

8 (42.1)

0.88b

Female

12 (57.2)

11 (57.9)

Inflammatory markers

IL-6 (pg/ml)

2.0 (0.8, 2.1)

2.2 (0.8, 6.4)

0.169c

CRP (mg/l)

7.0 (2.0, 10.0)

13.0 (5.0, 14.0)

0.014c

ESR (mm)

46.0 ± 26.0

50.7 ± 28.5

0.586a

Lipid profile

Cholesterol (mg/dl)

167.7 ± 38.4

206.8 ± 61.4

0.024a

Triglyceride (mg/dl)

170.0 (112.5184.0)

134.0 (103.0, 195.0)

0.989c

Liver function

SGPT (IU/l)

16.0 (12.0, 22.0)

16.0 (15.0, 26.0)

0.216c

SGOT (IU/l)

17.0 (12.5, 22.0)

20.0 (13.0, 38.0)

0.278c

Renal function

Renal Kt/V

0.3 (0.0, 1.1)

0.3 (0.1, 1.3)

0.592c

Urine volume (ml)

300.0 (0.0,1400.0)

500.0 (200.0,1000.0)

0.670c

nPCR

0.7 ± 0.2

0.8 ± 0.2

0.385a

Albumin (gr/dl)

4.3 ± 0.7

4.2 ± 0.5

0.515a

Peritoneal function

Peritoneal KTV

1.4 ± 0.4

1.5 ± 0.4

0.836a

Ultrafiltration (ml)

830.4 ± 495.9

887.9 ± 620.8

0.747a

Potassium (mEq/l)

4.3 ± 0.6

4.5 ± 0.6

0.295a

Phosphor (mg/dl)

5.2 ± 0.7

4.9 ± 1.1

0.245a

Calcium (mg/dl)

9.8 ± 0.7

9.7 ± 1.1

0.582a

Ferritin (ng/ml)

400.6 ± 332.5

319.8 ± 224.5

0.974a

Uric acid (mg/dl)

6.5 ± 1.0

5.6 ± 1.3

0.017a

Hemoglobin (g/dl)

11.4 (10.1–15.0)

11.7 (6.4–16.7)

0.97c

Other markers

Parathormon (pg/ml)

106.0 (49.0–171.0)

108.0 (70.0–138.0)

0.78c

Homocysteine (mcmol/l)

17.5 (12.3, 30.1)

22.7 (18.2, 42.0)

0.076c

Drug History

Calcitriol

7 (41.2)

10 (58.8)

0.33b

Statins

8 (34.8)

15 (65.2)

0.012b

ACE Inh/ ARB

6 (28.6)

6 (31.6)

1.0b

Furosemide

21 (100)

19 (100)

-b

Aldactone

0 (0)

0 (0)

-b

Beta blocker

1 (4.8)

0 (0)

1.0b

  1. IL-6 Interleukin 6, CRP C-reactive protein, ESR erythrocyte sedimentation rate, SGPT serum glutamic pyruvic transaminase, SGOT serum glutamic-oxaloacetic transaminase, and n-PCR: normalized protein catabolic rate
  2. avalues are presented as mean ± SD and compared by Independent T-test
  3. bValues are presented as number (%) and compared by chi square test
  4. cvalues are presented as median (IQR) and compared by Mann-Whitney Test