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Table 4 Within Group Comparison of Biochemical Characteristics of Patients in Control or Garlic group

From: Evaluating the effect of garlic extract on serum inflammatory markers of peritoneal dialysis patients: a randomized double-blind clinical trial study

Variable

Control group (N = 21)

Garlic group (N = 19)

Before

After

P-value

Before

After

P-value

IM

IL-6 (pg/ml)

2.0 (0.8, 2.1)

0.6 (0.6, 0.8)

0.002a

2.2 (0.8, 6.4)

0.7 (0.6, 1.2)

<  0.001a

CRP(mg/l)

7.0 (2.0, 10.0)

6.0 (3.7, 7.5)

0.547a

13.0 (5.0, 14.0)

2.0 (1.0, 9.0)

<  0.001a

ESR (mm)

46.0 ± 26.0

45.3 ± 22.3

0.797b

50.7 ± 28.5

35.4 ± 21.7

0.021b

LP

Cholesterol (mg/dl)

167.7 ± 38.4

153.6 ± 31.6

0.048b

206.8 ± 61.4

187.6 ± 36.9

0.053b

Triglyceride (mg/dl)

170.0 (112.5, 184.0)

146.0 (131.5, 186.5)

0.601a

134.0 (103, 195.0)

137.0 (90.0, 200.0)

0.334a

LF

SGPT (iu/l)

16.0 (12.0, 22.0)

16.0 (10.0, 21.0)

0.342 a

16.0 (15.0, 26.0)

19.0 (15.0, 22.0)

0.197 a

SGOT (iu/l)

17.0 (12.5, 22.0)

16.0 (11.0, 22.0)

0.422a

20.0 (13.0, 38.0)

20.0 (13.0, 22.0)

0.120 a

RF

Renal Kt/V

0.3 (0.0, 1.1)

0.3 (0.0–2.2)

0.599a

0.3 (0.1, 1.3)

0.3 (0.0–4.6)

0.155a

Urine volume (ml)

300.0 (0.0, 1400.0)

500.0 (0.0, 1550.0)

0.141a

500.0 (200.0, 1000.0)

500.0 (200.0, 1000.0)

0.267a

nPCR

0.7 ± 0.2

0.8 ± 0.2

0.423b

0.8 ± 0.2

0.8 ± 0.2

0.861b

Albumin

4.3 ± 0.7

4.2 ± 0.7

0.285b

4.2 ± 0.5

4.0 ± 0.5

0.051b

PF

Peritoneal KTV

1.4 ± 0.4

1.4 ± 0.5

0.438b

1.5 ± 0.4

1.4 ± 0.4

0.136b

Ultrafiltration (ml)

830.4 ± 495.9

1085.7 ± 589.3

0.004b

887.9 ± 620.8

973.2 ± 523.6

0.398b

Potassium (mEq/l)

4.3 ± 0.6

4.2 ± 0.5

0.920b

4.5 ± 0.6

4.7 ± 0.6

0.184b

Phosphor (mg/dl)

5.2 ± 0.7

5.3 ± 1.1

0.560b

4.9 ± 1.1

5.1 ± 1.3

0.179b

Calcium (mg/dl)

9.8 ± 0.7

10.0 ± 0.7

0.426b

9.7 ± 1.1

9.6 ± 0.7

0.871b

Ferritin(ng/ml)

400.6 ± 332.5

394.5 ± 381.9

0.805b

319.8 ± 224.5

280.3 ± 190.6

0.224b

Uric acid (mg/dl)

6.5 ± 1.0

6.5 ± 1.4

0.733b

5.6 ± 1.3

6.1 ± 1.4

0.035b

OM

Parathormon (pg/ml)

106.0 (49.0, 171.0)

180.0 (77.5, 209.0)

0.092

108.0 (70.0, 138.0)

130.0 (85.0, 230.0)

0.018

Homocysteine (mcmol/l)

17.5 (12.3, 30.1)

12.0 (9.0, 21.3)

0.035

22.7 (18.2, 42.0)

16.0 (10.8, 25.0)

<  0.001

  1. IM Inflammatory Markers, LP Lipid Profile, LF Liver Function, RF Renal Function, PF Peritoneal Function, IL-6 Interleukin 6, CRP C-Reactive Protein, ESR Erythrocyte Sedimentation Rate, SGPT Serum Glutamic Pyruvic Transaminase, SGOT Serum Glutamic-Oxaloacetic Transaminase; and n-PCR: normalized Protein Catabolic Rate
  2. avalues are presented as median (IQR) and compared by Wilcoxon Test
  3. bvalues are presented as mean ± SD and compared by Paired T-test