Table 3 Comparison of metabolic parameters at the beginning and at the end of follow up for kidney donors, matched-controls and healthy control group

BMI, kg/m²

Baseline

25.64 ± 3.4^a

25.3 ± 3.3^a

25 ± 2.7^b

0.003

LDFU

26.3 ± 4.19^a

25.8 ± 3.8^a

24.6 ± 3.7^b

< 0.001

Delta BMI

+ 0.65 ± 1.4^a

+ 0.41 ± 1.9^a

−0.3 ± 2.7^b

< 0.001

HDL, mg/dl

Baseline

51.3 ± 10.2^b

58.1 ± 14^a

55.8 ± 14^a

< 0.001

LDFU

54.4 ± 13.1^b

57.3 ± 14.2^a

55 ± 14.5^a

< 0.001

Delta HDL

+ 3.1 ± 13.8^b

− 0.7 ± 9.3^a

− 0.6 ± 9.3^a

< 0.001

LDL, mg/dl

Baseline

109.8 ± 23.2^b

117.3 ± 32.9^a

121.6 ± 30^a

< 0.001

LDFU

110.5 ± 28.4

111.1 ± 29.6

112.9 ± 27.4

0.340

Delta LDL

+ 0.73 ± 22.2

− 5.9 ± 26.9^a

−7.9 ± 28.6^a

< 0.001

TG, mg/dl

Baseline

111.1 ± 42.4^a

99.3 ± 57^b

108.9 ± 62.4^a

0.025

LDFU

117.1 ± 66.7^b

102.2 ± 62.4^a

106.9 ± 60.3^a

0.011

Delta TG

15.9 ± 51.5^b

5.1 ± 59.5^a

3.96 ± 63.4^a

0.019

SBP, mmHg

Baseline

121.6 ± 11.5^a

117.4 ± 13.3^b

119.6 ± 13.7^a

0.008

LDFU

126.6 ± 12.6^b

122.2 ± 14.6^a

123.1 ± 14.8^a

0.002

Delta SBP

5.1 ± 12

4.8 ± 11.7

3.7 ± 13.9

0.214

DBP, mmHg

Baseline

74.2 ± 8^a

73.9 ± 7.1^a

75.5 ± 7.8^b

0.001

LDFU

76.6 ± 7.9

75.4 ± 8.6

76.9 ± 9.3

0.082

Delta DBP

2.4 ± 8.5

1.55 ± 8.1

1.29 ± 9.5

0.255

HbA1C, %

Baseline

5.3 ± 0.43^b

5.26 ± 0.4^a

5.23 ± 0.4^b

0.002

LDFU

5.52 ± 0.5

5.5 ± 0.9

5.45 ± 0.46^a

0.006

Delta A1C

0.16 ± 0.5

0.19 ± 0.34

0.18 ± 0.26

0.760

Hypertension, %

Baseline

10.9

10.7

12.8

0.491

New onset

11.8

7.9

10.6

0.311

Metabolic syndrome, %

Baseline

5.2

3.8

3.3

0.216

New onset

21.9

13.1

15.1

0.032

Diabetes mellitus, %

Baseline

0

0

0

1

New onset

5.8

3.3

2.5

0.019

MACE, %

LDFU

1.9

0.5

4.9

< 0.001