Fig. 2

Plots of natural cubic splines including zero ischaemia to estimate the correlation between ischaemia time and (a) the relative (%) change in eGFR from baseline at time A (highest change in eGFR during the planned hospital stay prior to discharge (median, 1 day p.o.; IQR, 1–2) in model 1, (b) at time D (median, 13 months p.o.; IQR, 12–15) in model 2, (c) correlation between ischaemia time and the risk of AKI within 48 h p.o. in model 3 and its interaction with baseline renal function, respectively, and (d) correlation between ischaemia time and the risk of new-onset CKD stage ≥3 at time D. CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate; p.o., postoperatively; IQR, interquartile range