Table 2 Uric acid and renal pathological features

 age

38.67 ± 15.51

34.87 ± 11.53

<0.001

37.64 ± 14.99

38.91 ± 11.54

41.15 ± 9.54

0.55

 SBP

126.42 ± 17.55

127.74 ± 18.84

0.33

126.24 ± 17.79

131.18 ± 15.83△

142.17 ± 24.07#

0.001

 DBP

77.62 ± 11.98

79.23 ± 13.29

0.09

77.67 ± 12.29

81.05 ± 10.00△

88.08 ± 18.46

0.002

 UA

365.8 ± 102.2

394.3 ± 107.1

<0.001

367.0 ± 101.3

436.6 ± 114.1△

469.1 ± 103.0#

<0.001

 Cr

81.5 ± 52.7

92.7 ± 43.2

0.002

78.1 ± 40.7

146.2 ± 78.0△

221.8 ± 117.4#

<0.001

 eGFR

101.0 ± 30.4

89.2 ± 32.7

<0.001

102.0 ± 28.7

54.5 ± 23.5△

35.3 ± 18.1#ο

<0.001

 Urea

6.3 ± 3.7

7.2 ± 3.6

<0.001

6.2 ± 3.3

9.9 ± 5.6△

14.0 ± 5.5#

<0.001

 Alb

32.0 ± 9.8

37.1 ± 7.3

<0.001

33.0 ± 9.7

35.2 ± 7.4

35.6 ± 6.1

0.12

 24 h-u-pro

1.7 (0.4, 4.3)

1.5 (0.7, 2.8)

<0.001

1.6 (0.5, 4.0)

1.9 (1.0, 3.6)

3.7 (1.9, 4.6)

0.89

IgAN(n = 429)

(n = 237)

(n = 192)

(n = 369)

(n = 51)

(n = 9)

 age

35.23 ± 12.30

33.22 ± 10.25

0.07

34.09 ± 11.77

35.73 ± 9.73

36.78 ± 6.03

0.51

 SBP

126.73 ± 16.64

125.43 ± 18.53

0.48

125.21 ± 17.48

130.74 ± 15.12

136.88 ± 24.86

0.03

 DBP

77.35 ± 11.30

78.16 ± 13.13

0.53

76.95 ± 12.06

81.53 ± 10.09△

87.00 ± 19.03

0.006

 UA

374.6 ± 101.2

392.0 ± 109.5

0.09

373.1 ± 101.1

435.3 ± 115.3△

464.9 ± 97.2#

<0.001

 Cr

89.7 ± 56.6

91.0 ± 42.8

0.79

79.6 ± 33.0

152.4 ± 86.2△

177.6 ± 57.4#

<0.001

 eGFR

94.9 ± 33.0

90.7 ± 32.6

0.19

99.6 ± 29.2

53.9 ± 24.4△

42.2 ± 16.4#

<0.001

 Urea

6.6 ± 3.7

7.1 ± 3.7

0.11

6.2 ± 2.8

10.1 ± 6.0△

13.6 ± 4.5#

<0.001

 Alb

37.7 ± 7.5

38.6 ± 5.6

0.17

38.4 ± 6.7

36.1 ± 6.9△

34.9 ± 4.5

0.02

 24 h-u-pro

1.0 (0.4, 2.0)

1.4 (0.7, 2.5)

0.52

1.0 (0.5, 2.1)

2.0 (0.9, 4.0)△

3.7 (2.0, 4.8)

<0.001

non-IgAN (n = 641)

(n = 575)

(n = 66)

(n = 620)

(n = 17)

(n = 4)

 age

40.09 ± 16.45

39.73 ± 13.60

0.84

39.75 ± 16.25

48.47 ± 11.49△

51.00 ± 8.98

0.03

 SBP

126.31 ± 17.90

133.89 ± 18.40

0.002

126.81 ± 17.94

132.50 ± 18.40

152.75 ± 21.42#ο

0.009

 DBP

77.72 ± 12.24

82.08 ± 13.38

0.009

78.07 ± 12.41

79.57 ± 9.95

90.25 ± 19.87

0.13

 UA

362.2 ± 102.4

401. ± 100.3

0.003

363.4 ± 101.4

440.4 ± 113.6△

478.6 ± 130.7#

<0.001

 Cr

78.1 ± 50.6

97.7 ± 44.5

0.003

77.3 ± 44.7

127.3 ± 41.5△

321.3 ± 165.3

<0.001

 eGFR

103.5 ± 28.9

84.7 ± 32.6

<0.001

103.4 ± 28.3

56.4 ± 20.9△

19.8 ± 11.3#ο

<0.001

 Urea

6.2 ± 3.7

7.3 ± 3.4

0.02

6.2 ± 3.6

9.5 ± 3.9△

14.7 ± 8.0

<0.001

 Alb

29.6 ± 9.7

32.6 ± 9.5

0.02

29.8 ± 9.7

32.6 ± 8.4

37.1 ± 9.6

0.17

 24 h-u-pro

2.3 (0.4, 5.1)

1.8 (1.0, 4.5)

0.44

2.3 (0.4, 5.1)

1.6 (1.1, 4.8)

3.3 (1.8, 3.3)

0.86