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Table 2 Characteristics of the female participants grouped according to serum uric acid levels

From: Higher serum uric acid level is inversely associated with renal function assessed by cystatin C in a Japanese general population without chronic kidney disease: the KOBE study

 

Serum uric acid quartile

P for trend

1st (low)

2nd

3rd

4th (high)

Women (n = 765)

 Number of participants

204

172

195

194

 

 Serum uric acid (mg/dL)

≤3.8

3.9–4.3

4.4–4.9

≥5.0

 

 eGFR (mL/min/1. 73m2), mean (SD)

98.1 (16.0)

91.0 (14.2)

89.5 (14.1)

84.1 (13.5)

<  0.001

 Age (years), mean (SD)

56.3 (9.2)

58.1 (8.6)

57.5 (8.7)

59.7 (7.9)

<  0.001

 BMI (kg/m2), mean (SD)

20.0 (2.1)

21.0 (2.5)

20.8 (2.6)

22.1 (3.1)

<  0.001

 SBP (mmHg), mean (SD)

109 (15)

113 (16)

114 (17)

117 (18)

<  0.001

 DBP (mmHg), mean (SD)

66 (9)

69 (10)

69 (11)

72 (11)

<  0.001

 HbA1c (%), mean (SD)

5.6 (0.6)

5.5 (0.4)

5.5 (0.3)

5.6 (0.4)

0.865

 HDL-C (mg/dL), mean (SD)

72 (15)

72 (15)

71 (15)

71 (17)

0.279

 LDL-C (mg/dL), mean (SD)

129 (27)

136 (29)

133 (30)

139 (28)

0.005

 TG (mg/dL), median (IQR)

63 (49, 89)

70 (58, 105)

68 (64, 120)

82 (74, 154)

<  0.001

 Postmenopause, n (%)

136 (67)

140 (81)

148 (76)

170 (88)

<  0.001

 Current smoker, n (%)

6 (3)

3 (2)

4 (2)

2 (1)

0.213

 Current alcohol drinker, n (%)

62 (30)

58 (34)

85 (44)

75 (39)

0.023

 Current alcohol intake, ethanol (g/day)a, median (IQR)

5 (3, 13)

7 (2, 14)

7 (3, 13)

11 (3.4, 17)

0.559

 Estimated salt intake, g/day (SD)

8.2 (1.8)

8.5 (1.8)

8.1 (1.7)

8.2 (1.9)

0.655

  1. eGFR Estimated glomerular filtration rate, BMI Body mass index, SBP Systolic blood pressure, DBP Diastolic blood pressure, HDL-C High-density lipoprotein cholesterol, LDL-C Low-density lipoprotein cholesterol, TG Triglyceride, IQR Interquartile range. aCurrent drinker only