Fig. 6

Multivariable-adjusted odds ratio of metabolic syndrome according to levels of serum klotho. A serum klotho level of 518 pg/mL (ROC curve cut-off value) was taken as the reference point (OR = 1.00). The adjusted OR of MS was significantly increased at serum klotho levels of < 518 pg/mL. The model was adjusted for age, sex, eGFR, and overt proteinuria. The solid line represents the multivariable-adjusted ORs of MS according to levels of eGFR. The dashed lines indicate 95% confidence intervals. Overt proteinuria, 24-hour urine protein > 500 mg/day; ROC, receiver operating characteristic; eGFR, estimated glomerular filtration rate; OR, odds ratio; MS, metabolic syndrome