Skip to main content

Table 5 The associations between histopathological changes (i, t, v, ah, ci, cg, ct, cv, mm) in kidney allografts and rs763780 IL17F gene polymorphism

From: IL17A and IL17F genes polymorphisms are associated with histopathological changes in transplanted kidney

Biopsy parameter and genotypes

Grade 0

n %

Grade 1

n %

Grade 2

n %

Grade 3

n %

Mean ± SD

M-W test p for comparison TTvsTC

(i) n = 72

 TT

20

29.85

22

32.84

13

19.40

12

17.91

1.25 ± 1.08

0.43

 TC

0

0.00

3

60.00

1

20.00

1

20.00

1.60 ± 0.89

  

(t) n = 64

 TT

17

27.87

24

39.34

13

21.31

7

11.48

1.16 ± 0.97

0.89

 TC

0

0.00

3

100.0

0

0.00

0

0.00

1.00 ± 0.00

  

(v) n = 57

 TT

47

90.38

3

5.77

1

1.92

1

1.92

0.15 ± 0.54

0.49

 TC

5

100.0

0

0.00

0

0.00

0

0.00

0.00 ± 0.00

  

(ah) n = 68

 TT

21

33.33

30

47.62

11

17.46

1

1.59

0.87 ± 0.75

0.34

 TC

1

20.00

2

40.00

2

40.00

0

0.00

1.20 ± 0.84

  

(ci) n = 68

 TT

35

55.56

18

28.57

8

12.70

2

3.17

0.64 ± 0.83

0.017

 TC

0

0.00

3

60.00

1

20.00

1

20.00

1.60 ± 0.89

  

(cg) n = 55

 TT

44

88.00

5

10.00

–

1

2.00

0.16 ± 0.51

0.65

 TC

4

80.00

1

20.00

–

0

0.00

0.20 ± 0.45

  

(ct) n = 68

 TT

10

15.87

37

58.73

11

17.46

5

7.94

1.18 ± 0.79

0.09

 TC

0

0.00

2

40.00

2

40.00

1

20.00

1.80 ± 0.84

  

(cv) n = 51

 TT

28

60.42

6

12.50

6

12.50

7

14.58

0.83 ± 1.15

0.75

 TC

3

75.00

0

0.00

0

0.00

1

25.00

0.75 ± 1.50

  

(mm) n = 60

 TT

30

54.55

15

27.27

5

9.09

5

9.09

0.73 ± 0.97

0.72

 TC

3

60.00

0

0.00

0

0.00

2

40.00

1.20 ± 1.64

  
  1. p value calculated with the Mann-Whitney’s (M-W) test
  2. i – interstitial infiltration, t – tubulitis, v – intimal arteritis, ah – arteriolar hyaline thickening, ci – interstitial fibrosis, cg – glomerulopathy, ct – tubular atrophy, cv – fibrous intimal thickening, mm – mesangial matrix increase