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Table 2 PCA/multivariate Analysis models for urine

From: Meprin β metalloproteases associated with differential metabolite profiles in the plasma and urine of mice with type 1 diabetes and diabetic nephropathy

  Model # of Compounds Total # Samples # of Components R2X R2Y Q2 # Samples in STZ # Samples in NaC
Positive PCA All Samples 3513 54 5 0.781   0.663   
PCA 4 wks 3513 24 2 0.711   0.627   
PCA WT STZ v WT NaC 4 wk 3513 13 2 0.783   0.676   
OPLSDA WT STZ v WT NaC 4 wk 3513 13 1 + 1 0.775 0.993 0.981 9 4
PCA βKO STZ v βKO NaC 4wk 3513 11 2 0.770   0.634   
OPLSDA βKO STZ v βKO NaC 4wk 3513 11 1 + 0 0.598 0.596 0.444 8 3
PCA 8 wks 3513 24 4 0.803   0.641   
PCA WT STZ v WT NaC 8 wk 3513 13 2 0.774   0.648   
OPLSDA WT STZ v WT NaC 8 wk 3513 13 1 + 1 0.642 0.937 0.916 8 5
PCA βKO STZ v βKO NaC 8wk 3513 11 3 0.839   0.546   
OPLSDA βKO STZ v βKO NaC 8wk 3513 11 1 + 4 0.893 0.999 0.841 6 5
Negative PCA All Samples 4116 53 8 0.753   0.486   
PCA 4 wks 4116 24 4 0.692   0.477   
PCA WT STZ v WT NaC 4 wk 4116 13 2 0.632   0.453   
OPLSDA WT STZ v WT NaC 4 wk 4116 13 1 + 3 0.73 1 0.983 9 4
PCA βKO STZ v βKO NaC 4wk 4116 11 2 0.566   0.254   
OPLSDA βKO STZ v βKO NaC 4wk 4116 11 1 + 0 0.333 0.644 0.451 8 3
PCA 8 wk 4116 24 4 0.646   0.327   
PCA WT STZ v WT NaC 8 wk 4116 13 4 0.767   0.311   
OPLSDA WT STZ v WT NaC 8 wk 4116 13 1 + 0 0.409 0.953 0.921 8 5
PCA βKO STZ v βKO NaC 8wk 4116 11 2 0.574   0.174   
OPLSDA βKO STZ v βKO NaC 8wk 4116 11 1 + 6 0.894 1 0.816 6 5
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