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Table 2 Demographic and baseline characteristics at start of CRRT and events during or after CRRT according to successful or unsuccessful discontinuation

From: Predictors of short-term successful discontinuation of continuous renal replacement therapy: results from a prospective multicentre study

 

All patients n = 92

Successful stop CRRT n = 61 (66%)

Unsuccessful stop CRRT n = 31 (34%)

P-value

Age (years)

66 [55, 74]

62 (13)

64 (14)

0.275

Male gender, nr (%)

55 (60)

38 (62)

17 (55)

0.491

Weight (kg)

82 (16)

84 (17)

79 (15)

0.153

BMI (kg/m2)

25.7 [23.5, 30.3]

26.5 [23.9, 32.1]

25.1 [22.9, 27.7]

0.146

Previous kidney disease, nr (%)

20 (22)

10 (16)

10 (32)

0.081

Preadmission creatinine, μmol/L

96 [74, 127]

101 (39)

96 [71, 139]

0.599

Preadmission eGFR (CKD-EPI), (ml/min/1.73m2)

67.8 (26.2)

69.5 (25.1)

64.1 (46.0)

0.375

Cause of AKI, nr (%)

 Sepsis

34 (37)

19 (31)

15 (48)

0.058

 Toxic

4 (4)

3 (5)

1 (3)

 

 Primary renal disease

2 (2)

0 (0)

2 (7)

 

 Ischemic/ other

52 (57)

39 (64)

13 (42)

 

Reason for ICU admission, nr (%)

 Post-operative

32 (35)

20 (33)

12 (39)

0.185

 Respiratory failure

15 (16)

10 (17)

5 (16)

 

 Sepsis

17 (19)

8 (13)

9 (29)

 

 Post cardiac arrest

7 (7)

7 (11)

0 (0)

 

 Cardiac failure

9 (10)

7 (11)

2 (6)

 

 Other

12 (13)

9 (15)

3 (10)

 

SAPS III admission

53 (16)

52 (15)

55 (18)

0.470

APACHE III admission

89 (31)

88 (29)

91 (36)

0.624

Mechanical ventilation at initiation of CRRT

69 (75)

45 (74)

24 (77)

0.702

Vasopressor at initiation of CRRT

74 (80)

49 (80)

25 (81)

0.971

Events during or after CRRT

 Infection day −4 until day 0, nr (%)

21 (23)

14 (24)

7 (23)

0.936

 Infection day 0 until day 7 after stop CRRT, nr (%)

17 (19)

9 (15)

8 (26)

0.197

 Citrate anticoagulation, nr (%)

74 (80)

49 (80)

25 (81)

0.971

 Nephrotoxic medication or IV contrast, day −4 until day 0, nr (%)

68 (75)

43 (71)

25 (81)

0.350

 Nephrotoxic medication or IV contrast, day 0 until day 7 after stop, nr (%)

62 (67)

43 (71)

19 (61)

0.374

 Diuretics day 0 until day 2, nr (%)

73 (80)

45 (74)

28 (90)

0.064

  1. Mean (standard deviation) for normally distributed variables, median [25th and 75th percentile] for non-normally distributed variables, number (percentage) when appropriate
  2. BMI body mass index, eGFR estimated glomerular filtration rate, CKD-EPI chronic kidney disease epidemiology collaboration, AKI acute kidney injury, ICU intensive care unit, SAPS III simplified acute physiology score, APACHE III acute physiology and chronic health evaluation score, CRRT continuous renal replacement therapy
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BMC Nephrology

ISSN: 1471-2369

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