Definitive TC- related bloodstream infection | Probable TC-related bloodstream infection |
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At least one positive blood culture drawn from a peripheral vein or the arterial line up to 48 h after TC removal if performed And at least one of the following criteria: Positive quantitative broth culture of TC tip (Brun Buisson technique) > 102 UFC/mL with the same microorganism Or Positive culture of the exit-site discharge with the same microorganism Or Positive blood culture drawn from one of the lumen of the TC following aspiration of the lock with the same microorganism and with a concentration ratio > 3 or a differential time to positivity > 2 h in relation to the blood culture sampled from the peripheral vein Or Resolution of signs of infection within 48 h following TC removal with no other apparent source of sepsis other than the TC | At least one positive blood culture drawn from a peripheral vein or the arterial line for a pathogenic microorganism (S. aureus, enterobacteriaceae, pseudomonas sp., Candida sp.) Or At least two positive blood cultures from a peripheral vein or the arterial line Or At least one positive blood culture from a peripheral vein or the arterial line in an immunocompromised patient Up to 48 h after TC removal if performed No other apparent source of sepsis other than the TC |