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Table 1 Characteristics of the derivation cohort

From: Temporal validation of the CT-PIRP prognostic model for mortality and renal replacement therapy initiation in chronic kidney disease patients

  Nodes
All nodes 1 2 3 4 5 6 7
N (%) 2265 (100.0) 230 (10.1) 378 (16.1) 152 (4.4) 264 (10.9) 90 (3.9) 410 (19.3) 741 (35.2)
eGFR change, mean ± sd −1.33 ± 5.16 −3.66 ± 6.44 − 1.37 ± 4.29 − 2.83 ± 4.05 − 1.34 ± 3.89 − 2.97 ± 6.31 .06 ± 7.02 −.84 ± 3.85
baseline eGFR, mean ± sd 29.0 ± 13.1 46.7 ± 13.3 23.2 ± 6.3 18.9 ± 6.8 34.0 ± 16.6 31.9 ± 14.4 24.5 ± 9.0 28.9 ± 10.9
PO4, mean ± sd 3.83 ± .83 3.60 ± .72 3.62 ± .47 5.10 ± .71 3.80 ± .88 3.99 ± .65 4.03 ± .82 3.59 ± .71
Age, mean ± sd 71.2 ± 12.9 63.8 ± 14.4 70.3 ± 13.0 65.7 ± 13.9 54.9 ± 11.7 61.1 ± 6.1 78.6 ± 6.0 78.2 ± 5.8
Diabetes, n(%) 739 (32.6) 104 (45.2) 141 (37.3) 67 (44.0) 0 (0) 90 (100.0) 118 (28.8) 219 (29.6)
Male gender, n(%) 1475 (65.1) 170 (73.9) 259 (68.5) 73 (48.0) 171 (64.8) 61 (67.8) 0 (0) 741 (100.0)
Number of drugs prescribed, mean ± sda 8.02 ± 3.26 8.18 ± 3.0 8.84 ± 2.9 8.91 ± 2.6 6.44 ± 3.1 8.44 ± 3.9 8.24 ± 3.4 7.76 ± 3.3
Annual number of hospital admissions, median; IQRb 0.69; 0.78 0.67; 0.86 0.81; 0.89 1.09; 1.06 0.49; 0.80 0.94; 1.02 0.60; 0.67 0.67; 0.69
RRT events, n(%) 536 (23.8) 40 (17.4) 122 (32.3) 91 (60.7) 82 (31.2) 27 (30.0) 60 (14.6) 115 (15.6)
Deaths, n(%) 657 (29.0) 36 (15.7) 105 (27.8) 36 (24.0) 18 (6.8) 21 (23.3) 147 (35.9) 294 (39.8)
Event-free median survival time (years) 5.20 6.00 4.46 2.05 6.00 5.22 5.13 5.18
Node ranking (RRT/death)   −−/−− +/+ ++/+ +/−− +/− −−/+ −−/+
  1. Abbreviations: sd = standard deviation, IQR = interquartile range
  2. a ANOVA post-hoc comparisons: node 4 < all other nodes; node 7 < nodes 2, 3
  3. b Conover-Iman test post-hoc comparison with Holm adjustment: node 3 > nodes 1, 2, 4, 6, 7; nodes 2, 5 > nodes 1, 4, 6, 7; nodes 1, 7 > 4
  4. + high risk, ++very high risk, − low risk, −- very low risk