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Table 1 Characteristics of the derivation cohort

From: Temporal validation of the CT-PIRP prognostic model for mortality and renal replacement therapy initiation in chronic kidney disease patients

 

Nodes

All nodes

1

2

3

4

5

6

7

N (%)

2265 (100.0)

230 (10.1)

378 (16.1)

152 (4.4)

264 (10.9)

90 (3.9)

410 (19.3)

741 (35.2)

eGFR change, mean ± sd

−1.33 ± 5.16

−3.66 ± 6.44

− 1.37 ± 4.29

− 2.83 ± 4.05

− 1.34 ± 3.89

− 2.97 ± 6.31

.06 ± 7.02

−.84 ± 3.85

baseline eGFR, mean ± sd

29.0 ± 13.1

46.7 ± 13.3

23.2 ± 6.3

18.9 ± 6.8

34.0 ± 16.6

31.9 ± 14.4

24.5 ± 9.0

28.9 ± 10.9

PO4, mean ± sd

3.83 ± .83

3.60 ± .72

3.62 ± .47

5.10 ± .71

3.80 ± .88

3.99 ± .65

4.03 ± .82

3.59 ± .71

Age, mean ± sd

71.2 ± 12.9

63.8 ± 14.4

70.3 ± 13.0

65.7 ± 13.9

54.9 ± 11.7

61.1 ± 6.1

78.6 ± 6.0

78.2 ± 5.8

Diabetes, n(%)

739 (32.6)

104 (45.2)

141 (37.3)

67 (44.0)

0 (0)

90 (100.0)

118 (28.8)

219 (29.6)

Male gender, n(%)

1475 (65.1)

170 (73.9)

259 (68.5)

73 (48.0)

171 (64.8)

61 (67.8)

0 (0)

741 (100.0)

Number of drugs prescribed, mean ± sda

8.02 ± 3.26

8.18 ± 3.0

8.84 ± 2.9

8.91 ± 2.6

6.44 ± 3.1

8.44 ± 3.9

8.24 ± 3.4

7.76 ± 3.3

Annual number of hospital admissions, median; IQRb

0.69; 0.78

0.67; 0.86

0.81; 0.89

1.09; 1.06

0.49; 0.80

0.94; 1.02

0.60; 0.67

0.67; 0.69

RRT events, n(%)

536 (23.8)

40 (17.4)

122 (32.3)

91 (60.7)

82 (31.2)

27 (30.0)

60 (14.6)

115 (15.6)

Deaths, n(%)

657 (29.0)

36 (15.7)

105 (27.8)

36 (24.0)

18 (6.8)

21 (23.3)

147 (35.9)

294 (39.8)

Event-free median survival time (years)

5.20

6.00

4.46

2.05

6.00

5.22

5.13

5.18

Node ranking (RRT/death)

 

−−/−−

+/+

++/+

+/−−

+/−

−−/+

−−/+

  1. Abbreviations: sd = standard deviation, IQR = interquartile range
  2. a ANOVA post-hoc comparisons: node 4 < all other nodes; node 7 < nodes 2, 3
  3. b Conover-Iman test post-hoc comparison with Holm adjustment: node 3 > nodes 1, 2, 4, 6, 7; nodes 2, 5 > nodes 1, 4, 6, 7; nodes 1, 7 > 4
  4. + high risk, ++very high risk, − low risk, −- very low risk