Table 1 Baseline characteristics of participants according to the pregnancy outcome
Never-pregnant (n = 10) | Miscarriage (n = 9) | Clinical pregnancy(n = 21) | P value | |
|---|---|---|---|---|
Age (years) | 34.5 (29–42) | 36 (30–39) | 33 (27–41) | 0.44 |
Duration tried to concieve (months) | 44 (16–108) | 48 (6–96) | 22 (6–96) | 0.1 |
Years since transplantation (years) | 4 (2–8)a | 7 (2–18)a | 5.5 (1–14) | 0.08 |
SBP (mmHg) | 123 (113–144) | 135 (100–162) | 120 (100–145) | 0.44 |
DBP (mmHg) | 80 (70–92) | 76 (60–96) | 72 (58–96) | 0.2 |
Serum BUN (mg/dL) | 18.85 (8.4–34.4) | 25.4 (18.7–37.2)b | 17.2 (10.2–35.3)b | 0.04 |
eGFR | 55.08 (22–96.6) | 39 (9.0–76)b | 60.72 (37–89.7)b | 0.02 |
Hypertension | 0.59 | |||
No | 4 (40%) | 2 (22.2%) | 5 (23.8%) | |
Yes | 6 (60%) | 7 (77.8%) | 16 (76.2%) | |
Diabetes melitus | 0.04 | |||
No | 8 (80%) | 9 (100%) | 21 (100%) | |
Yes | 2 (20%) | 0 | 0 | |
Graft rejection | 0.01 | |||
No | 7 (70%) | 3 (33.32%) | 19 (90.5%) | |
Yes | 3 (30%) | 6 (66.7%)b | 2 (9.5%)b | |
Cause of ESRD | 0.13 | |||
Unknown | 1 (10%) | 2 (22.2%) | 5 (25%) | |
SLE | 1 (10%) | 3 (33.3%) | 0 | |
Glomerulonephritis | 4 (40%) | 2 (22.2%) | 9 (42.9%) | |
Ig A nephropathy | 2 (20%) | 1 (11.1%) | 7 (33.3%) | |
Congenital anomaly | 1 (10%) | 1 (11.1%) | 0 | |
Diabetes melitus | 1 (10%) | 0 | 0 | |
Immunosuppressant regimen | 0.3 | |||
CI | 1 (10%) | 2 (22.2%) | 6 (28.6%) | |
CI + ST + AP | 6 (60%) | 1 (11.1%) | 5 (23.8%) | |
CI + ST | 3 (30%) | 5 (55.6%) | 9 (42.9%) | |
CI + AP | 0 | 1 (11.1%) | 1 (4.8%) | |
Immunosuppressant use | ||||
CyA | 3 (30%) | 2 (22.2%) | 9 (45%) | 0.52 |
TAC | 6 (60%) | 7 (77.8%) | 12 (57.1%) | 0.55 |
DFZ | 9 (90%) | 1 (11.1%) | 2 (9.5%) | < 0.0001 |
Pred | 2 (20%) | 6 (66.7%) | 13 (61.9%) | 0.06 |
Aza | 5 (50%) | 0 | 2 (9.5%) | 0.01 |
MMF | 2 (20%) | 2 (22.2%) | 4 (19%) | 0.98 |