Table 2 Pattern of corticosteroid therapy and subsequent outcome in difficult nephrotic syndrome (n = 176)
Parameter | Number | Percentage |
Dose of initial oral steroid treatment | ||
Prednisolone (60 mg/m2/day) | 176 | 100 |
Timing of daily oral prednisolone | ||
Single morning dose | 130 | 73.86 |
Divided doses | 46 | 26.13 |
Duration of daily prednisolone | ||
4 weeks | 108 | 61.36 |
6 weeks | 50 | 28.40 |
8 weeks | 18 | 10.22 |
Total duration of initial prednisolone | ||
3 months | 57 | 32.38 |
4 months | 92 | 52.27 |
6 months | 27 | 15.34 |
Categories based on steroid response and frequency of relapses | ||
Steroid sensitive | 130 | 73.86 |
Frequent relapser | 75 | 57.69 |
Steroid dependent | 55 | 42.30 |
Steroid resistant | 46 | 26.13 |
Steroid toxicity in 105 children with FR/SD and SRNS | ||
Cushingoid | 81 | 46.02 |
Severe infection | 18 | 10.22 |
Steroid psychosis | 3 | 1.7 |
Hypertension | 3 | 1.7 |