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Table 2 Analysis of association between EDN3 single-nucleotide polymorphisms (SNPs) and hospitalized infection events

From: Association of endothelin genetic variants and hospitalized infection complications in end-stage renal disease (ESRD) patients

 

Genotype

Infection (n = 106)

(%)

Without infection (n = 84)

(%)

Genotype model

Dominant model

Recessive model

Allelic model

P value

P value

P value

P value

rs742650

TT

1

1.2

1

1.7

0.4215

0.8156

0.2224

0.9896

CT

18

20.9

9

15.5

    

CC

67

77.9

48

82.8

    

rs260740

GG

0

0.0

1

1.7

0.3925

0.8894

0.1864

0.9252

GT

29

30.9

14

23.3

    

TT

65

69.1

45

75.0

    

rs260741

AA

6

7.1

6

11.1

0.5823

0.4068

0.3609

0.3127

AG

30

35.3

20

37.0

    

GG

49

57.6

28

51.9

    

rs6064764

CC

2

2.1

1

1.3

0.1387

0.0568

0.9998

0.0938

CT

21

22.1

7

9.3

    

TT

72

75.8

67

89.3

    

rs197173

TT

6

6.7

9

13.8

0.5902

0.9957

0.3368

0.6674

GT

31

34.8

20

30.8

    

GG

52

58.4

36

55.4

    

rs197174

GG

2

2.1

3

4.9

0.2504

0.2100

0.1494

0.1253

GA

17

18.1

11

18.0

    

AA

75

79.8

47

77.0

    

rs882345

GG

4

4.3

0

0.0

0.0168

0.2688

0.0350

0.7671

GA

9

9.7

12

18.5

    

AA

80

86.0

53

81.5

    

rs926632

CC

3

3.2

2

2.9

0.0096

0.0095

0.6393

0.0534

CT

9

9.5

18

25.7

    

TT

83

87.4

50

71.4

    

rs3026575

AA

0

0.0

1

1.5

0.0754

0.2642

0.0269

0.1212

AG

6

6.4

5

7.7

    

GG

88

93.6

59

90.8

    

rs11570352

TT

3

2.9

5

6.0

0.3515

0.7034

0.2324

0.4364

TC

4

3.8

1

1.2

    

CC

97

93.3

78

92.9

    
  1. The P value was adjusted for age, sex, diabetes, hemoglobin, albumin, and the cause of ESRD. The P values of < 0.05 are shown in bold
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BMC Nephrology

ISSN: 1471-2369

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