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Table 3 Analysis of association between EDN3 single-nucleotide polymorphisms (SNPs) and hospitalized bacteremia events

From: Association of endothelin genetic variants and hospitalized infection complications in end-stage renal disease (ESRD) patients

 

Genotype

Bacteremia (n = 24)

(%)

Without bacteremia (n = 84)

(%)

Genotype model

Dominant model

Recessive model

Allelic model

P value

P value

P value

P value

rs742650

TT

0

0

1

1.7

0.4983

0.3770

0.5773

0.4870

CT

6

30.0

9

15.5

    

CC

14

70.0

48

82.8

    

rs260740

GG

0

0.0

1

1.7

0.5886

0.9802

0.3185

0.8360

GT

7

33.3

14

23.3

    

TT

14

66.7

45

75.0

    

rs260741

AA

0

0.0

6

11.1

0.0203

0.0165

0.0350

0.0077

AG

4

21.1

20

37.0

    

GG

15

78.9

28

51.9

    

rs6064764

CC

1

4.5

1

1.3

0.0905

0.0286

0.5282

0.0447

CT

6

27.3

7

9.3

    

TT

15

68.2

67

89.3

    

rs197173

TT

0

0.0

9

13.8

0.0447

0.0393

0.0465

0.0188

GT

4

19.0

20

30.8

    

GG

17

81.0

36

55.4

    

rs197174

GG

0

0.0

3

4.9

0.3176

0.3178

0.1659

0.2094

GA

5

25.0

11

18.0

    

AA

15

75.0

47

77.0

    

rs882345

GG

0

0.0

0

0.0

0.1100

NA

NA

NA

GA

1

4.8

12

18.5

    

AA

20

95.2

53

81.5

    

rs926632

CC

0

0.0

2

2.9

0.0395

0.0123

0.3256

0.0112

CT

1

4.8

18

25.7

    

TT

20

95.2

50

71.4

    

rs3026575

AA

0

0.0

1

1.5

0.8634

0.5878

0.9999

0.5879

AG

1

4.8

5

7.7

    

GG

20

95.2

59

90.8

    

rs11570352

TT

1

4.2

5

6.0

0.6086

0.4834

0.6859

0.5661

TC

0

0.0

1

1.2

    

CC

23

95.8

78

92.9

    
  1. The P value was adjusted for age, sex, diabetes, hemoglobin, albumin, and the cause of ESRD. The P values of < 0.05 are shown in bold