Skip to main content

Table 1 Clinical variables of the 120 patients with low or high arterial stiffness

From: Serum osteoprotegerin is an independent marker of central arterial stiffness as assessed using carotid–femoral pulse wave velocity in hemodialysis patients: a cross sectional study

Characteristics

All Patients

(n = 120)

Low Arterial Stiffness

Group (n = 67)

High Arterial Stiffness Group (n = 53)

p value

Demographics

 Age (years)

63.3 ± 13.7

61.7 ± 14.1

65.4 ± 13.2

0.144

 Female gender

60 (50.0)

35 (52.2)

25 (47.2)

0.851

 HD duration (years)

4.7 (2.0–9.8)

5.8 (1.8–11.1)

4.6 (2.3–7.1)

0.434

Examination

 Height (cm)

159.6 ± 8.5

158.9 ± 8.9

160.6 ± 8.0

0.290

 Body weight (kg)

61.5 ± 14.6

63.3 ± 16.3

65.5 ± 13.8

0.444

 BMI (kg/m2)

25.1 ± 5.0

24.9 ± 5.4

25.3 ± 4.5

0.681

 SBP (mmHg)

142.2 ± 25.2

137.9 ± 26.3

147.5 ± 22.8

0.038*

 DBP (mmHg)

76.8 ± 16.6

76.2 ± 15.5

77.5 ± 18.0

0.669

 cfPWV (m/s)

9.30 (7.63–12.37)

7.80 (7.10–8.80)

12.6 (11.40–15.25)

< 0.001*

Laboratory data

 Total cholesterol (mg/dL)

144.2 ± 32.3

145.0 ± 35.8

143.2 ± 27.6

0.582

 Glucose (mg/dL)

131.5 (110.3–172.8)

129.0 (110.0–163.0)

134.0 (110.5–185.0)

0.235

 BUN (mg/dL)

61.9 ± 14.5

61.9 ± 13.1

61.9 ± 16.2

0.978

 Creatinine (mg/dL)

9.2 ± 2.0

9.3 ± 2.0

9.0 ± 2.0

0.397

 Corrected calcium (mg/dL)

8.8 ± 0.6

8.6 ± 0.7

9.0 ± 0.8

0.007*

 Phosphorus (mg/dL)

4.8 ± 1.2

4.8 ± 1.3

4.9 ± 1.2

0.573

 C-reactive protein (mg/dL)

0.31 (0.08–0.89)

0.30 (0.08–1.01)

0.34 (0.09–0.74)

0.830

 Intact PTH (pg/mL)

190.0 (58.5–355.3)

239.3 (114.4–372.5)

141.1 (44.4–339.9)

0.066

 OPG (pg/L)

286.2 (209.0–343.6)

247.9 (187.8–332.2)

316.3 (246.2–413.3)

< 0.001*

 Kt/V (Gotch)

1.34 ± 0.17

1.35 ± 0.18

1.34 ± 0.16

0.717

Comorbid conditions

 Diabetes mellitus, s (%)

56 (46.7)

22 (32.8)

33 (64.2)

0.001*

 Hypertension, n (%)

60 (50.0)

29 (43.3)

31 (58.5)

0.098

 CAD, n (%)

78 (65.0)

39 (58.2)

39 (73.6)

0.079

Medications

 ACEIs or ARBs, n (%)

41 (34.2)

21 (31.3)

20 (37.7)

0.463

 β-Blockers, n (%)

33 (20.6)

19 (28.4)

14 (26.4)

0.813

 CCBs, n (%)

44 (27.5)

27 (40.3)

17 (32.1)

0.353

 Statins, n (%)

17 (14.2)

7 (10.4)

10 (18.9)

0.189

  1. Values for continuous variables are shown as mean ± standard deviation and analyzed by Student’s t-test; variables not normally distributed are shown as median and interquartile range and analyzed by the Mann–Whitney U test; values for categorical variables are presented as number (%) and analyzed by the chi-square test or Fisher’s exact test
  2. HD hemodialysis, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, cfPWV carotid–femoral pulse wave velocity, BUN blood urea nitrogen, PTH parathyroid hormone, OPG osteoprotegerin, Kt/V fractional clearance index for urea, CAD coronary artery disease, ACEIs angiotensin-converting enzyme inhibitors, ARBs angiotensin receptor blockers, CCBs calcium channel blockers
  3. *p < 0.05 is considered as statistically significant