Fig. 3

Effect of advanced administration of anisodamine/atropine on kidneys in rats subjected to glycerol-induced AKI. a Serum Scr in groups of male SD rats (n = 6) given intramuscular injections of 50% glycerol (10 mL/kg) with anisodamine (1 mg/kg) and atropine (0.05 mg/kg) by intraperitoneal injection 20 min before glycerol treatment. The control group did not receive any treatment. Data are expressed as the mean ± SEM (n = 6). #, statistically significantly different from respective 0 h controls; *, statistically significantly different from rats receiving glycerol treatment alone at the corresponding time point (P < 0.05). b Serum BUN in groups of male SD rats (n = 6) given intramuscular injections of 50% glycerol (10 mL/kg), with anisodamine (1 mg/kg) and atropine (0.05 mg/kg) by intraperitoneal injection 20 min before glycerol treatment. The control group did not receive any treatment. Data are expressed as the mean ± SEM (n = 6). #, statistically significantly different from respective 0 h controls; *, statistically significantly different from rats receiving glycerol treatment alone at the corresponding time point (P < 0.05). c Serum CK in groups of male SD rats (n = 6) injected intramuscularly with 50% glycerol (10 mL/kg), with anisodamine (1 mg/kg) and atropine (0.05 mg/kg) by intraperitoneal injection 20 min before glycerol treatment. The control group did not receive any treatment. Data are expressed as the mean ± S.E. (n = 6). #, statistically significantly different from respective 0 h controls (P < 0.05). *, statistically significantly different from rats receiving glycerol treatment alone at the corresponding time point (P < 0.05)