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Table 1 Baseline characteristics of total study subjects

From: Impact of Pneumocystis jirovecii pneumonia on kidney transplant outcome

Variables

Total

(n = 1502)

PCP negative

(n = 1434)

PCP positive

(n = 68)

P

Age (years)

45.3 ± 13.0

45.1 ± 13.0

48.3 ± 14.4

0.053

Female (%)

39.1

39.9

23.5

0.007

Body mass index (kg/m2)

22.5 ± 3.7

22.5 ± 3.8

22.6 ± 2.6

0.969

Donor type (%)

   

0.124

 Living

67.4

67.8

58.8

 

 Deceased

32.6

32.2

41.2

0.391

  Standard criteria donor

25.4

25.2

29.4

 

  Expanded criteria donor

7.2

7.0

11.8

 

Pre-transplant dialysis (%)

   

0.005

 Preemptive

15.6

15.3

22.1

 

 Hemodialysis

65.2

66.0

47.1

 

 Peritoneal dialysis

19.2

18.7

30.9

 

Duration of dialysis (months)

40.1 ± 47.7

40.0 ± 47.5

42.9 ± 51.9

0.650

Re-transplantation

7.2

7.2

7.4

0.958

ABO-incompatible (%)

7.4

6.8

19.1

<  0.001

HLA mismatch (numbers)

3.1 ± 1.7

3.1 ± 1.7

3.1 ± 1.7

0.983

 HLA-A

0.9 ± 0.7

0.9 ± 0.7

1.0 ± 0.8

0.344

 HLA-B

1.2 ± 0.7

1.2 ± 0.7

1.2 ± 0.8

0.861

 HLA-DR

1.0 ± 0.7

1.0 ± 0.7

0.9 ± 0.7

0.291

Calcineurin inhibitor (%)

   

0.260

 None

3.1

3.0

5.9

 

 Cyclosporine

13.0

13.2

8.8

 

 Tacrolimus

83.9

83.8

85.3

 

mTOR inhibitor (%)

1.9

1.9

2.9

0.535

Induction regimen (%)

   

0.022

 None

19.0

19.6

7.4

 

 Basliximab

79.6

78.9

92.6

 

 Antithymocyte globulin

1.4

1.5

0

 

Desensitization (%)

11.5

10.9

22.1

0.005

Diabetes mellitus (%)

19.0

18.9

22.1

0.517

Hypertension (%)

89.9

89.5

98.5

0.016

DMN for kidney failure (%)

16.4

16.3

19.1

0.543

Positivity for CMV (%)

21.4

19.5

60.3

<  0.001

Oral prophylactic antibiotics (%)

18.8

19.2

10.3

0.067

  1. Comparisons were evaluated between PCP-negative and PCP-positive groups
  2. Abbreviations: PCP Pneumocystis jirovecii pneumonia, HLA human leukocyte antigen, DMN diabetic nephropathy, mTOR mammalian target of rapamycin, CMV cytomegalovirus