Table 1 Results of assays performed before and after treatment in the patient with IgG4-RKD
Time | First attack (March 2015) | After the first treatment (February 2016) | Second attack (August 2016) | Recent (March 2018) |
|---|---|---|---|---|
Item | ||||
Urinary protein/red blood cells | 3+/+ | −/− | 3+/− | −/− |
24-h urine protein (0.024–0.15 g/24 h) | 5.226↑ | 0.665↑ | 11.78↑ | 1.308↑ |
Hemoglobin (110-170 g/L) | 157 | 166 | 137 | 154 |
Eosinophils (0–0.3 × 109/L) | 0.07 | 0.05 | 0.02 | 0.09 |
Serum creatinine (40-120 μmol/L) | 96 | 77 | 340↑ | 89 |
Total blood protein (60–80 g/L) | 50.8↓ | 70 | 38.3↓ | 64 |
Albumin (35–55 g/L) | 18.9↓ | 41.8 | 13.7↓ | 43.7 |
Serum IgG (8–16 g/L) | 5↓ | 8.2 | 1.62↓ | 8.4 |
Serum IgG4 (3-201 mg/dl) | 25.5 | 118 | ||
Serum C3 (0.8–1.6 g/L) | 0.89 | 1.1 | 0.38↓ | 1.21 |
Serum C4 (0.2–0.4 g/L) | 0.06↓ | 0.3 | 0.09↓ | 0.23 |
PLA2R | Negative | Negative | ||
Kidney sizes | Left kidney 12.7 cm × 5.0 cm, and right kidney 10.2 cm × 4.0 cm | Left kidney 13.3 cm × 5.8 cm, and right kidney 11.7 cm × 5.4 cm |