Fig. 4From: The PPARγ agonist pioglitazone prevents TGF-β induced renal fibrosis by repressing EGR-1 and STAT3Proposed novel mechanism how the PPARγ agonist pioglitazone attenuates TGF-β1 induced renal fibrosis. Our study shows that PPARγ agonist pioglitazone repressed the transcription factors EGR-1, STAT3, and AP-1 (cFos, cJun), all of which are important signaling mediators in the pathomechanisms of TGF-β1 driven renal fibrosisBack to article page