Skip to main content

Table 2 Methodological analyses in saliva lab tests for creatinine, uric acid, and potassium in control group: blind duplicates, site of collection, day-to-day variability, time of collection, and freezing/thawing effect (mean ± SEM)

From: Saliva for assessing creatinine, uric acid, and potassium in nephropathic patients

  

P

R

Blind duplicates

first duplicate

second duplicate

  

 Creatinine, μmol/L

11.5 ± 3.9

11.7 ± 1.5

0.321

0.748 §

 Uric acid, μmol/L

261 ± 166

251 ± 145

0.187

0.993*

 Potassium, mmol/L

22.2 ± 6.6

22.5 ± 5.9

0.349

0.997*

Site of collection

right vestibulum

left vestibulum

 

 Creatinine, μmol/L

11.7 ± 4.1

11.4 ± 1.6

0.628

0.728 §

 Uric acid, μmol/L

262 ± 74

264 ± 65

0.865

0.991*

 Potassium, mmol/L

23.2 ± 7.5

23.6 ± 5.8

0.791

0.898*

Day-to-day variability

first day

second day

 

 Creatinine, μmol/L

11.5 ± 3.9

11.5 ± 2.0

0.723

0.735 §

 Uric acid, μmol/L

261 ± 166

255 ± 165

0.790

0.677 §

 Potassium, mmol/L

22.2 ± 6.6

25.4 ± 6.7

0.389

0.620 §

Time of collection

standard sample

mid-morning sample

 

 Creatinine, μmol/L

11.5 ± 3.9

9.1 ± 1.5

0.038

0.765

 Uric acid, μmol/L

261 ± 166

184 ± 102

< 0.001

0.915

 Potassium, mmol/L

22.2 ± 6.6

18.7 ± 5.9

< 0.001

0.728

Freezing/thawing effects

standard sample

frozen/thawed sample

 

 Creatinine, μmol/L

11.5 ± 3.9

10.5 ± 1.4

0.488

0.899

 Uric acid, μmol/L

261 ± 166

216 ± 118

< 0.001

0.818

 Potassium, mmol/L

22.2 ± 6.6

21.4 ± 5.7

0.389

0.829

  1. Non-stimulated fresh saliva collected early in the morning after an overnight fast with the use of a synthetic swap
  2. Control group N = 15 (14 for creatinine)
  3. * P < 0.001, § P ≤ 0.01