Table 4 Factors associated with renal non-recovery in patients with acute respiratory distress syndrome

 Stage I

Ref

Ref

Ref

Ref

Ref

Ref

 Stage II

5.00

2.24 to 11.98

< 0.001

5.71

2.17 to 14.98

< 0.001

 Stage III

40.38

17.31 to 103.73

< 0.001

45.85

16.27 to 129.2

< 0.001

Acute kidney injury onset, day^c

1.08

1.02 to 1.16

0.01

1.12

1.03 to 1.21

0.01

SOFA score^c

1.20

1.11 to 1.31

< 0.001

–

–

–

History of heart failure

0.33

0.13 to 0.82

0.02

–

–

–

History of active malignancies

3.26

1.67 to 6.79

< 0.001

4.02

1.59 to 10.15

0.003

Septic shock

3.61

2.12 to 6.24

< 0.001

3.20

1.52 to 6.76

0.002

Mean tidal volume on day 1–3, mL/kg PBW^c

1.31

1.08 to 1.61

0.01

1.41

1.05 to 1.90

0.02

Mean PEEP on day 1–3, cm H₂O^c

1.06

0.99 to 1.14

0.09

–

–

–

Continuous neuromuscular blocking agents

2.42

1.41 to 4.24

0.002

–

–

–

Inhaled vasodilators

1.95

1.07 to 3.7

0.03

–

–

–

Recruitment maneuvers

4.02

1.31 to 17.58

0.03

–

–

–

Antipsychotic drugs

0.61

0.36 to 1.02

0.06

–

–

–

Furosemide on day 2–7

0.48

0.28 to 0.82

0.01

–

–

–

Fluid overload on day 7, %^c

1.07

1.02 to 1.12

0.005

–

–

–