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Table 1 General characteristics of the study population at referral

From: Clinical characteristics and outcome of HIV infected patients with chronic kidney disease in Sub Saharan Africa: an example from Cameroon

Variables

Total

Gender

P

Stage

P

Male

Female

G3a

G3b

G4

G5

N (%)

156 (100.0)

80 (51.3)

76 (48.7)

 

13 (8.3)

20 (12.8)

32 (20.5)

91 (58.3)

 

Age (years), Mean ± SDa

45.4 ± 12.1

48.3 ± 11.8

42.4 ± 11.6

0.002

46.6 ± 14.9

49.0 ± 12.8

43.2 ± 12.7

45.3 ± 11.2

0.394

Age (years), Min-Max

22–82

25–82

22–72

 

26–72

28–70

25–82

22–77

 

Marital status, n (%)

 Married

87 (55.8)

58 (72.5)

29 (38.2)

 

9 (69.2)

9 (45.0)

17 (53.1)

52 (57.1)

 

 Single

53 (34.0)

17 (21.3)

36 (47.4)

 

3 (23.1)

8 (40.0)

13 (40.6)

29 (31.9)

 

 Divorced

2 (1.3)

1 (1.3)

1 (1.3)

 

0 (0.0)

0 (0.0)

1 (3.1)

1 (1.1)

 

 Widow

14 (9.0)

4 (5.0)

10 (13.2)

< 0.001

1 (7.7)

3 (15.0)

1 (3.1)

9 (9.9)

0.784

Employment status, n (%)

 Unemployed

56 (35.9)

11 (13.8)

45 (59.2)

 

6 (46.2)

4 (20.0)

12 (37.5)

34 (37.4)

 

 Public agent

10 (6.4)

8 (10.0)

2 (2.6)

 

0 (0.0)

1 (5.0)

1 (3.1)

8 (8.8)

 

 Private sector

37 (23.7)

29 (36.3)

8 (10.5)

 

5 (38.5)

5 (25.0)

8 (25.0)

19 (20.9)

 

 Informal sector

39 (25.0)

18 (22.5)

21 (27.6)

 

1 (77)

6 (300)

8 (25.0)

24 (26.4)

 

 Retired

14 (9.0)

14 (17.5)

0 (0.0)

< 0.001

1 (7.7)

6 (30.0)

8 (25.0)

24 (26.4)

0.548

Co morbidity, n (%)

 Hypertension

57 (36.5)

25 (31.6)

32 (42.1)

0.177

4 (33.3)

6 (30.0)

10 (31.3)

37 (40.7)

0.690

 Diabetes

28 (17.9)

18 (22.8)

10 (13.2)

0.119

2 (16.7)

6 (30.0)

7 (21.9)

13 (14.3)

0.372

 HCVb coinfection

12 (7.7)

7 (8.8)

5 (6.6)

0.611

1 (7.7)

2 (10.0)

1 (3.1)

8 (8.8)

0.742

 Chronic use of NSAIDc

9 (5.8)

4 (5.1)

5 (6.6)

0.744

1 (8.3)

1 (5.0)

1 (3.1)

6 (6.6)

0.876

 HBVd coinfection

6 (3.8)

5 (6.3)

1 (1.3)

0.211

0 (0.0)

2 (10.0)

3 (9.4)

1 (1.1)

0.070

Background nephropathy, n (%)

 HIVANe

43 (27.6)

26 (32.5)

17 (22.4)

 

4 (30.8)

5 (25.0)

6 (18.8)

28 (30.8)

 

 Chronic glomerulonephritis

24 (15.4)

9 (11.3)

15 (19.7)

 

1 (7.7)

5 (25.0)

5 (15.6)

13 (14.3)

 

 Diabetes

22 (14.1)

15 (18.8)

7 (9.2)

 

1 (7.7)

6 (30.0)

4 (12.5)

11 (12.1)

 

 Hypertension

21 (13.5)

7 (8.8)

14 (18.4)

 

3 (23.1)

2 (10.0)

12 (37.5)

21 (23.1)

 

 Chronic interstitial nephritis

7 (4.5)

3 (3.8)

4 (5.3)

 

1 (7.7)

0 (0.0)

1 (3.1)

5 (5.5)

 

 Polykystosis

1 (0.6)

1 (1.3)

0 (0.0)

 

0 (0.0)

1 (5.0)

0 (0.0)

0 (0.0)

 

 Unknown

38 (24.4)

19 (23.8)

19 (25.0)

0.139

3 (23.1)

2 (10.0)

12 (37.5)

21 (23.1)

0.242

Known HIVe infected, n (%)

109 (69.9)

56 (70.0)

53 (69.7)

0.971

8 (61.5)

16 (80.0)

21 (65.6)

64 (70.3)

 

HIV infection vintage (month)g

36 (11–96)

36 (12–108)

36 (10.3–96)

0.856

24 (1–144)

15 (4–48)

24 (7.5–60)

36 (12–108)

0.251

Use of cARTf, n (%)

76 (48.7)

36 (45.0)

40 (52.6)

0.340

7 (53.8)

10 (50.0)

11 (34.4)

48 (52.7)

 

Duration on cARTfg

36 (6.8–96)

36 (12–99)

36 (6–96)

0.879

40 (18.3–90)

8 (2–79.5)

48 (4–72)

36 (9.8–105)

0.797

Drug regimen, n (%), n = 76

 1st line

65 (85.5)

33 (91.7)

32 (80.0)

 

6 (85.7)

8 (80.0)

8 (72.7)

43 (89.6)

 

 2nd line

11 (14.5)

3 (8.3)

8 (20.0)

0.199

1 (14.3)

2 (20.0)

3 (27.3)

5 (10.4)

 

CD4 countg, n = 88

241 (117–438)

256 (138–387)

216 (96–535)

0.619

101 (66–376)

176.5 (137–333.3)

278 (117.3–549)

271 (120–451)

0.456

  1. Values in italics are significant (p value< 0.05)
  2. aSD Standard deviation, bHCV Hepatitis C virus, cNSAID Non-steroidal anti-inflammatory drugs, dHBV Hepatitis B virus, eHIVAN Human immuno-deficiency virus associated nephropathy, fcART Combined antiretroviral treatment; gMedian (1st-3th quartiles)