Table 1 Baseline parameters. Baseline clinical and biochemical parameters are shown of healthy subjects and patients with IgA nephropathy. Results are shown as mean ± standard deviation
Parameter | Healthy volunteers (n = 10) | IgAN group (n = 20) | p-value |
|---|---|---|---|
Age (years) | 46 ± 16 | 44 ± 16 | 0.72 |
Gender (% Male) | 60% | 70% | 0.58 |
Body mass index (kg/m2) | 24.7 ± 2.5 | 29.6 ± 6.6 | 0.04 |
Blood pressure (mmHg) | 117/71 ± 9/12 | 126/77 ± 12/7 | .06/.09 |
Mean number of Antihypertensive | 0.2 | 1.81 | 0.00 |
Total number of on ACE/ARB c | 1 | 17 | 0.00 |
CKD-EPI eGFR (ml/min/1.73m2) | 91.5 ± 9.1 | 62 ± 36 | 0.02 |
Serum creatinine (μmol/L) | 77 ± 12.2 | 151.7 ± 110 | 0.04 |
Protein Creatinine Ratio (mg/mmol) | 7.13 ± 4.0 | 158.1 ± 201.5 | 0.03 |
Haemoglobin (g/L) b | 140 ± 12 | 140 ± 16b | 0.99 |
Haematocrit (L/L)b | 0.419 ± 0.03 | 0.416 ± 0.04b | 0.84 |
T MEST score (number)a | |||
0 | 8 | ||
1 | 6 | ||
2 | 5 | ||
S MEST score (number)a | |||
0 | 4 | ||
1 | 15 | ||
CKD staging (number of patients) | |||
1 | 5 | ||
2 | 3 | ||
3 | 9 | ||
4 | 2 | ||
5 | 1 | ||