Table 2 Bivariate correlation between sclerostin levels and clinical parameters
Parameters | rs | P value | adjusted rs | P value |
|---|---|---|---|---|
Age (year) | 0.108 | 0.314 | ||
Sex-male | 0.266 | 0.011 | ||
Dialysis vintage (day) | 0.068 | 0.528 | 0.149 | 0.167 |
Weight (kg) | 0.210 | 0.048 | 0.087 | 0.427 |
Height (cm) | 0.256 | 0.016 | 0.101 | 0.359 |
Body mass index (kg/m2) | 0.108 | 0.312 | 0.060 | 0.580 |
Total Kt/V for urea | −0.072 | 0.505 | 0.010 | 0.926 |
Diabetes mellitus | 0.185 | 0.083 | 0.179 | 0.098 |
Hypertension | 0.089 | 0.407 | 0.091 | 0.402 |
Parathyroidectomy | 0.056 | 0.601 | 0.104 | 0.339 |
Anuria | 0.120 | 0.261 | 0.165 | 0.126 |
FGF-23 (pg/mL) | −0.066 | 0.540 | −0.127 | 0.242 |
DKK-1 (pg/mL) | 0.171 | 0.109 | 0.174 | 0.107 |
CTX (ng/mL) | −0.081 | 0.453 | −0.098 | 0.369 |
25(OH)-vitamin D (ng/mL) | 0.235 | 0.026 | 0.131 | 0.227 |
Osteocalcin (ng/mL) | −0.168 | 0.116 | −0.191 | 0.076 |
Intact PTH (pg/mL) | −0.300 | 0.004 | −0.357 | < 0.001 |
Urea nitrogen (mg/dL) | 0.074 | 0.492 | 0.054 | 0.620 |
Creatinine (mg/dL) | 0.295 | 0.005 | 0.262 | 0.014 |
Calcium (mg/dL) | −0.091 | 0.396 | − 0.110 | 0.309 |
Phosphorus (mg/dL) | −0.003 | 0.981 | −0.017 | 0.876 |
Magnesium (mg/dL) | −0.022 | 0.841 | −0.025 | 0.816 |
Albumin (g/dL) | 0.013 | 0.905 | −0.031 | 0.776 |
Alkaline phosphatase (U/L) | −0.201 | 0.059 | −0.214 | 0.047 |
Cholesterol (mg/dL) | −0.183 | 0.086 | −0.126 | 0.244 |
Triglyceride (mg/dL) | 0.010 | 0.927 | 0.047 | 0.664 |
Hemoglobin (g/dL) | 0.286 | 0.007 | 0.257 | 0.016 |
Glucose (mg/dL) | 0.287 | 0.007 | 0.291 | 0.006 |
Uric acid (mg/dL) | 0.180 | 0.091 | 0.183 | 0.089 |
hsCRP (mg/L) | −0.004 | 0.972 | 0.002 | 0.982 |
BMD, spine L1 to L4 (g/cm2) | 0.277 | 0.009 | 0.271 | 0.011 |
BMD spine T-score | 0.237 | 0.025 | 0.274 | 0.010 |
BMD spine Z-score | 0.232 | 0.029 | 0.237 | 0.027 |
Ankle brachial index | −0.095 | 0.377 | −0.170 | 0.119 |
Pulse wave velocity (m/s) | 0.031 | 0.776 | 0.067 | 0.537 |