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Fig. 2 | BMC Nephrology

Fig. 2

From: Membranoproliferative glomerulonephritis with deposition of monoclonal IgG evolved from polyclonal IgG: a case report with two consecutive renal biopsies

Fig. 2

Pathological findings of the second renal biopsy. a Frozen tissue on IF showed granular IgG deposition along the capillary wall and in the mesangial area. (× 200). b IF showed granular C3 deposition along the capillary wall and in the mesangial area. (× 200). c Immunohistiochemistry on paraffin tissue showed granular C4d deposition along the capillary wall and in the mesangial area. (×400). d IF showed trace κ light chain deposition. (× 200). e IF showed strong granular λ light chain deposition along the capillary wall and in the mesangial area. (× 200). f IF showed strong granular IgG3 deposition along the capillary wall and in the mesangial area. (× 200). g Light microscopy showed a MPGN pattern of the glomeruli. (periodic acid-Schiff staining, ×400). h Electron microscopy showed the electron-dense deposits in the mesangial, subendothelial and subepithelial areas of the glomeruli. (× 5000)

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