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Table 4 Influences of different therapy regimens on the renal recovery within 3 months

From: Pathological severity determines the renal recovery for anti-myeloperoxidase antibody-associated vasculitis requiring dialysis at disease onset: a retrospective study

 MP vs. PEPulse CTX vs. Oral CTX
MP (n = 26)PE (n = 14)P valuePulse CTX (n = 10)Oral CTX (n = 30)P value
MP/PE7/319/110.702
Pulse CTX/Oral CTX7/193/110.702
BVAS22.9 ± 6.219.9 ± 5.10.13223.4 ± 4.921.3 ± 6.20.333
eGFR (mL/min/1.73 m2)6.4 ± 2.06.2 ± 2.30.7746.6 ± 2.16.3 ± 2.10.646
Proteinuria (g/24 h)2.7 ± 1.73.3 ± 3.20.3842.8 ± 2.13.0 ± 2.50.848
Gross hematuria (Y/N)3/230/140.1861/92/280.729
Renal recovery (CR/PR/N)7/7/126/5/30.2973/4/310/8/120.715
Time for getting dialysis independence (days)41.4 ± 11.729.4 ± 15.60.03934.8 ± 11.136.3 ± 15.90.894
  1. BVAS Birmingham vasculitis activity score, CTX Cyclophosphamide, CR Complete remission, eGFR Estimated glomerular filtration rate, MP Methylprednisolone pulse therapy, PE Plasma exchange, PR Partial remission
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