Skip to main content

Table 4 Influences of different therapy regimens on the renal recovery within 3 months

From: Pathological severity determines the renal recovery for anti-myeloperoxidase antibody-associated vasculitis requiring dialysis at disease onset: a retrospective study

 

MP vs. PE

Pulse CTX vs. Oral CTX

MP (n = 26)

PE (n = 14)

P value

Pulse CTX (n = 10)

Oral CTX (n = 30)

P value

MP/PE

7/3

19/11

0.702

Pulse CTX/Oral CTX

7/19

3/11

0.702

BVAS

22.9 ± 6.2

19.9 ± 5.1

0.132

23.4 ± 4.9

21.3 ± 6.2

0.333

eGFR (mL/min/1.73 m2)

6.4 ± 2.0

6.2 ± 2.3

0.774

6.6 ± 2.1

6.3 ± 2.1

0.646

Proteinuria (g/24 h)

2.7 ± 1.7

3.3 ± 3.2

0.384

2.8 ± 2.1

3.0 ± 2.5

0.848

Gross hematuria (Y/N)

3/23

0/14

0.186

1/9

2/28

0.729

Renal recovery (CR/PR/N)

7/7/12

6/5/3

0.297

3/4/3

10/8/12

0.715

Time for getting dialysis independence (days)

41.4 ± 11.7

29.4 ± 15.6

0.039

34.8 ± 11.1

36.3 ± 15.9

0.894

  1. BVAS Birmingham vasculitis activity score, CTX Cyclophosphamide, CR Complete remission, eGFR Estimated glomerular filtration rate, MP Methylprednisolone pulse therapy, PE Plasma exchange, PR Partial remission