Table 2 SAEs and AEs in the HCQ and corticosteroid groups

SAEs

0.03

  0

92

86

  1

0

5

  ≥ 2

0

1

 Event details

  Death^a

1

  Severe infection

3

   Pneumonia^a

2

   Gastrointestinal infection

1

  Gastrointestinal bleeding^a

1

  New-onset diabetes mellitus

1

  Hyperosmolar hyperglycemia

1

AEs

< 0.001

  0

81

52

  1

6

19

  ≥ 2

3

15

 Event details

   Cardiovascular effects

    Palpitations^b

1

4

    Exertional dyspnea

0

1

   Gastrointestinal effects

    Liver dysfunction

1

5

    Nausea^b

1

1

    Abdominal discomfort/pain

0

5

    Bloating

0

3

    Constipation

0

1

   Bone and muscle effects

    Arthralgia

0

8

    Arthrocele

0

1

    Myalgia

0

2

    Muscle fasciculation

0

2

    Muscle enzyme elevation

0

1

    Numbness

0

1

    Hand tremors

0

1

    Ostealgia

0

1

   Neuropsychiatric effects

    Dizziness

0

1

    Insomnia

0

4

   Ophthalmologic effects

    Intraocular pressure elevation

1

0

    Blurred vision

0

2

    Ocular swelling pain

0

1

   Urogenital effects

    eGFR reduction

2

0

    Menstrual disorder

0

2

   Mucocutaneous effects

    Pruritus^c

2

0

    Skin pigmentation^b

1

0

    Ecchymosis

0

1

    Oral ulcer

0

1

    Acne

0

1

    Desquamation

1

0

    Papules

0

3

    Folliculitis

0

1

    Alopecia^c

1

1

   Hematologic effects

    Lymphocytopenia

0

1

   Anaphylactic effects

    Dyspnea^d

1

0

    Rashes^d

1

0