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Table 1 Demographic and clinical data of patients by type of donor and risk groups for antibody-mediated rejection

From: Effects of immunotherapy induction on outcome and graft survival of kidney-transplanted patients with different immunological risk of rejection

Variable

LD (n = 255)

DD (n = 214)

G1

G2

G3

G4

P value

G1

G2

G3

G4

P value

Number of patients

191 (74.90%)

41 (16.08%)

12 (4.71%)

11 (4.31%)

 

150 (70.09%)

34 (15.89%)

14 (6.54%)

16 (7.48%)

 

Gender

 Male

143 (74.87%)

13 (31.71%)

1 (8.33%)

4 (36.36%)

< 0.001

111 (74.00%)

25 (73.53%)

3 (21.43%)

7 (43.75%)

< 0.001

 Female

48 (25.13%)

28 (68.29%)

11 (91.67%)

7 (63.64%)

39 (26.00%)

9 (26.47%)

11 (78.57%)

9 (56.25%)

Age (years) ± SDV

41.49 ± 11.58

41.88 ± 11.45

38.33 ± 8.283

46.45 ± 12.396

0.396

48.50 ± 11.83

51.38 ± 14.67

45.64 ± 15.16

45.94 ± 13.68

0.377

ABO group (n = 467)

 O

94 (49.47%)

24 (58.54%)

5 (41.67%)

6 (54.55%)

0.559

68 (45.64%)

15 (44.12%)

5 (35.71%)

10 (62.50%)

0.891

 A

69 (36.32%)

12 (29.27%)

7 (58.33%)

3 (27.27%)

57 (38.26%)

13 (38.24%)

6 (42.86%)

3 (18.75%)

 B

23 (12.11%)

4 (9.76%)

0 (0%)

1 (9.09%)

11 (7.38%)

3 (8.82%)

2 (14.29%)

2 (12.50%)

 AB

4 (2.11%)

1 (2.44%)

0 (0%)

1 (9.09%)

13 (8.72%)

3 (8.82%)

1 (7.14%)

1 (6.25%)

Etiology of CKD

 Hypertensive nephropathy

16 (8.38%)

8 (19.51%)

1 (8.33%)

2 (18.18%)

0.616

28 (18.67%)

6 (17.65%)

2 (14.29%)

1 (6.25%)

0.246

 Diabetes mellitus

21 (10.99%)

3 (7.32%)

0 (0%)

1 (9.09%)

25 (16.67%)

4 (11.76%)

2 (14.29%)

3 (18.75%)

 Glomerulopathy

45 (23.56%)

9 (21.95%)

3 (25.00%)

1 (9.09%)

23 (15.33%)

9 (26.47%)

1 (7.14%)

1 (6.25%)

 Autosomal polycystic kidney disease

18 (9.42%)

3 (7.32%)

1 (8.33%)

1 (9.09%)

17 (11.33%)

3 (8.82%)

2 (14.29%)

1 (6.25%)

 Undetermined

83 (43.46%)

15 (36.59%)

5 (41.67%)

6 (54.55%)

54 (36.00%)

8 (23.53%)

7 (50.00%)

8 (50.00%)

 Others

8 (4.19%)

3 (7.32%)

2 (16.67%)

0 (0%)

3 (2.00%)

4 (11.76%)

0 (0%)

2 (12.50%)

Type of dialysis

 Hemodialysis

148 (77.49%)

36 (87.80%)

11 (91.67%)

11 (100.00%)

0.141

142 (94.67%)

32 (94.12%)

12 (85.71%)

16 (100.0%)

0.672

 Peritoneal dialysis

14 (7.33%)

1 (2.44%)

0 (0%)

0 (0%)

6 (4.00%)

1 (2.94%)

1 (7.14%)

0 (0%)

 Preemptive

29 (15.18%)

4 (9.76%)

1 (8.33%)

0 (0%)

2 (1.33%)

1 (2.94%)

1 (7.14%)

0 (0%)

Time in dialysis (mo) ± SDV

21.09 ± 24.12

34.93 ± 34.07

51.25 ± 65.06

30.45 ± 21.36

< 0.001

55.29 ± 40.13

52.91 ± 34.64

52.57 ± 27.28

64.88 ± 43.58

0.762

DGF

 Yes

–

–

–

 

–

94 (62.67%)

18 (52.94%)

6 (42.86%)

12 (75.00%)

0.227

 No

–

–

–

 

56 (37.33%)

16 (47.06%)

8 (57.14%)

4 (25.00%)

Cold ischemia time (h) ± SDV

–

–

–

 

–

16.74 ± 5.57

17.28 ± 6.72

14.91 ± 4.39

19.04 ± 5.72

0.272

Expanded criteria

–

–

–

       

 Yes

–

–

–

 

–

36 (24.00%)

3 (8.82%)

1 (7.14%)

7 (43.75%)

0.014

 No

–

–

–

 

114 (76.00%)

31 (91.18%)

13 (92.86%)

9 (56.25%)

  1. CKD chronic kidney disease, DGF delayed graft function
  2. P-values in boldface are statistically significant