Racial disparities in end-stage renal disease in a high-risk population: the Southern Community Cohort Study

BMC Nephrology

Table 3 Adjusted hazard ratios (HR) and 95% confidence intervals (CI) for the association between baseline characteristics and end-stage renal disease (ESRD), SCCS 2002–2009

	ESRD risk (unadjusted for eGFR)^a		ESRD risk (adjusted for eGFR)^b
	HR	95% CI	HR	95% CI
Black race (Ref: white)	2.64	1.72, 4.04	2.58	1.65, 4.03
Female (Ref: male)	0.51	0.38, 0.70	0.42	0.31, 0.58
Education <12th grade (Ref: ≥12th grade)	1.02	0.76, 1.37	0.96	0.70, 1.31
Income < $15,000 (Ref: ≥$15,000)	1.11	0.81, 1.50	0.97	0.71, 1.33
Ever Smoker (Ref. never)	0.81	0.59, 1.09	0.70	0.51, 0.96
Hypertension	3.30	2.13, 5.11	1.96	1.21, 3.19
Diabetes Duration (Ref: no diabetes)
< 10 years	4.04	2.75, 5.93	5.25	3.53, 7.81
10–19 years	12.57	8.44, 18.73	8.50	5.57, 12.96
≥ 20 years	16.00	10.17, 25.18	12.17	7.34, 20.16
Stroke, TIA	1.54	0.99, 2.40	1.80	1.16, 2.79
MI/Bypass	1.30	0.85, 1.99	0.98	0.63, 1.52

Abbreviations: CI confidence interval, eGFR estimated glomerular filtration rate, ESRD end-stage renal disease, HR hazard ratio, MI myocardial infarction, SCCS Southern Community Cohort Study, TIA transient ischemic attack
^aAll variables were included in the Cox regression model simultaneously, in addition to age and body mass index modeled as restricted cubic splines
^bAdditionally adjusted for eGFR at baseline

ISSN: 1471-2369