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Table 5 Interpretation of HBV results prior to vaccination (1B)

From: Clinical practice guideline management of blood borne viruses within the haemodialysis unit

HBsAg

anti-HBs titre

Anti-HBc

Interpretation

–

–

–

Not Immune

Has not been infected, but still at risk for possible future infection.

VACCINATE

–

+

+

Immune

Surface antibodies present due to previous infection, and now recovered.

VACCINE NOT NEEDED

–

+

–

Immune

Has already been vaccinated. Level of immunity will depend on titre.

REFER to medical staff if NO prior history of vaccination

VACCINE MAY / MAY NOT BE NEEDED

+

–

+

Hepatitis B Infection

Hepatitis B virus is present.

REFER to medical staff

VACCINE NOT NEEDED

–

–

+

Unclear

likely natural immunity - vaccination may be indicated particularly in immunocompromised patients