Table 2 Baseline characteristics, dialysis and hemodynamic data stratified by hemodynamic profile. Data are presented as n(%), mean ± SD or median [Q1,Q3]
Index | Normal n = 10 (6.9%) | Low CPI n = 47 (32.6%) | Low TPRI n = 18 (12.5%) | High CPI n = 18 (12.5%) | High TPRI n = 51 (35.4%) | P-value |
|---|---|---|---|---|---|---|
Demographics | ||||||
Male | 6 (60.0%) | 30 (63.8%) | 10 (55.6%) | 7 (38.9%) | 28 (54.9%) | 0.50 |
Age (y) | 68.4 ± 11.7 | 71.6 ± 12.0 | 69.1 ± 7.6 | 61.9 ± 10.8 | 64.4 ± 13.0 | < 0.01 |
Weight (kg) | 73.8 ± 19.1 | 75.4 ± 15.3 | 76.4 ± 16.6 | 66.4 ± 18.7 | 72.9 ± 15.4 | 0.22 |
BMI (kg/m2) | 27.4 ± 5.3 | 27.3 ± 5.7 | 26.2 ± 5.3 | 25.1 ± 7.1 | 26.9 ± 5.3 | 0.67 |
Diabetes | 5 (50.0%) | 27 (58.7%) | 9 (50.0%) | 7 (38.9%) | 28 (56.0%) | 0.69 |
Heart failure | 1 (10.0%) | 14 (29.8%) | 6 (33.3%) | 3 (16.7%) | 12 (23.5%) | 0.54 |
Fluid removal data | ||||||
Duration (hh:mm) | 3:19 ± 0:53 | 3:49 ± 0:42 | 3:40 ± 0:23 | 3:47 ± 0:35 | 3:46 ± 0:41 | 0.28 |
TFR (ml) | 2421 ± 1091 | 2505 ± 829 | 2150 ± 836 | 2008 ± 1112 | 2553 ± 1039 | 0.21 |
UF (ml/kg/h) | 10.7 ± 4.6 | 8.8 ± 3.3 | 8.9 ± 3.2 | 8.0 ± 4.3 | 9.6 ± 4.0 | 0.36 |
Pretreatment hemodynamic | ||||||
SBP (mmHg) | 133 ± 19 | 130 ± 20 | 119 ± 13 | 156 ± 16 | 150 ± 23 | < 0.001 |
DBP (mmHg) | 69 ± 9 | 63 ± 10 | 61 ± 11 | 78 ± 11 | 78 ± 13 | < 0.001 |
MAP (mmHg) | 90 ± 10 | 85 ± 11 | 80 ± 10 | 104 ± 10 | 102 ± 13 | < 0.001 |
CI (l/min/m2) | 3.32 [2.85,3.82] | 2.31 [1.96,2.80] | 4.03 [3.40,4.49] | 3.65 [3.23,4.24] | 2.61 [1.96,3.08] | < 0.001 |
CPI (W/m2) | 0.61 [0.57,0.76] | 0.42 0.36,0.51] | 0.70 [0.57,0.84] | 0.85 [0.71,1.02] | 0.56 [0.43,0.72] | < 0.001 |
TPRI (dyn*sec/cm5*m2) | 2022 [1885,2909] | 2985 [2391,3775] | 1593 [1433,1858] | 2192 [2019.2592] | 33,022 [2668,4177] | < 0.001 |
Intradialytic nadir hemodynamic | ||||||
SBP (mmHg) | 126 ± 19 | 111 ± 16 | 105 ± 17 | 158 ± 20 | 157 ± 23 | < 0.001 |
DBP (mmHg) | 68 ± 9 | 54 ± 9 | 53 ± 9 | 79 ± 15 | 84 ± 12 | < 0.001 |
MAP (mmHg) | 87 ± 12 | 72 ± 9 | 70 ± 10 | 105 ± 12 | 108 ± 12 | < 0.001 |
CI (l/min/m2) | 3.02 [2.68,3.80] | 1.81 [1.48,2.07] | 4.37 [3.80.5.00] | 4.45 [3.7, 4.99] | 1.99 [1.77,2.37] | < 0.001 |
CPI (W/m2) | 0.59 [0.50,0.70] | 0.28 [0.24,0.34] | 0.68 [0.56,0.82] | 0.99 [0.92,1.13] | 0.46 [0.40,0.59] | < 0.001 |
TPRI (dyn*sec/cm5*m2) | 2210 [1816,2909] | 3219 [2795,4211] | 1321 [1149,1397] | 11,843 [1629,2928] | 44,215 [3508,4744] | < 0.001 |
Post treatment hemodynamic | ||||||
SBP (mmHg) | 124 ± 16 | 122 ± 20 | 110 ± 16 | 147 ± 25 | 150 ± 26 | < 0.001 |
DBP (mmHg) | 71 ± 10 | 59 ± 8 | 58 ± 11 | 78 ± 12 | 77 ± 11 | < 0.001 |
MAP (mmHg) | 88 ± 10 | 79 ± 10 | 75 ± 11 | 101 ± 13 | 101 ± 14 | < 0.001 |
CI (l/min/m2) | 3.07 [2.88,3.70] | 2.30 [1.88,2.70] | 3.81 [3.35,4.31] | 3.75 [3.22,4.62] | 2.42 [1.92,2.83]) | < 0.001 |
CPI (W/m2) | 0.69 [0.57,0.60] | 0.40 [0.31,0.50] | 0.60 [0.50,0.81] | 0.87 [0.76, 1.00] | 0.55 [0.44,0.66] | < 0.001 |
TPRI (dyn*sec/cm5*m2) | 2275 [1807,2730] | 2796 [2461,3756] | 1494 [1357,1724] | 11,992 [1761,2744] | 3404 [2812,4243] | < 0.001 |