Table 1 Inclusion Criteria for the CURE-CKD Registry

Chronic Kidney Disease [15,16,17]

1. At least two eGFR (CKD-EPI equation or Schwartz) measurements <60 mL/min/1.73m² at least 90 days apart, or

2. At least two laboratory measurements at least 90 days apart in which albuminuria was indicated; albumin to creatinine ratio ≥30 mg/g, or total urine protein ≥150 mg/g, or

3. At least one encounter (inpatient or outpatient) with an ICD-9 or ICD-10 diagnosis code indicating chronic kidney disease is present

Hypertension [18]

1. At least two vital sign measurements >14 days apart with a systolic blood pressure ≥140 mm Hg or diastolic blood pressure ≥90 mm Hg, or

2. At least one encounter (inpatient or outpatient) with an ICD-9 or ICD-10 diagnosis code indicating hypertension is present

Diabetes Mellitus [19, 20]

1. Any qualifying laboratory result:

 a. one HbA1c ≥6.5%, or

 b. two random blood glucose measurements ≥200 mg/dL, at least 1 day, but no more than 2 years apart, or

 c. two fasting blood glucose measurements ≥126 mg/dl, at least 1 day, but no more than 2 years apart, or

2. At least one medication record with a pharmaceutical class (i.e. anti-glycemic medications) for treating diabetes mellitus (excludes individuals diagnosed with PCOS taking metformin), or

3. At least two outpatient ICD-9 or ICD-10 diagnosis codes indicating diabetes mellitus is present, or

4. At least one inpatient ICD-9 or ICD-10 diagnosis code indicating diabetes mellitus is present

Pre-Diabetes Mellitus

1. Any qualifying laboratory result:

 a. one HbA1c 5.7–6.4%, or

 b. two random blood glucose measurements 140–199 mg/dL, at least 1 day, but no more than 2 years apart, or

 c. two fasting blood glucose measurements 100–125 mg/dl, at least 1 day, but not more than 2 years apart, or

2. At least one encounter (inpatient or outpatient) with an ICD-9 or ICD-10 diagnosis code indicating pre-diabetes mellitus