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Table 2 Progression of PNGAL and UNGAL in AKI, max KDIGO stage, need for RRT and mortality groups

From: Early detection of acute kidney injury in the perioperative period of liver transplant with neutrophil gelatinase-associated lipocalin

PNGAL values
  Pre-op. (100) Intra-op. (95) 6 h (90) 18 h (87) 24 h (86) 48 h (74)
 no AKI / mild AKI 172
(102–331)
196
(117–310)
138
(93–282)
170
(117–252)
156
(113–243)
116
(89–221)
 severe AKI 185
(114–287)
232
(158–364)
265
(177–429)
326
(180–616)
356
(215–666)
369
(235–535)
 P 0.82 0.50 0.047 0.004 < 0.0001 < 0.0001
 no-RRT 166 (79–270) 192
(127–323)
183
(86–281)
168
(120–249)
173
(122–286)
134 (91–248)
 need RRT 204 (115–465) 318
(204–407)
341
(242–510)
459
(306–749)
608
(333–749)
481 (292–689)
 P 0.27 0.015 < 0.0001 < 0.0001 < 0.0001 < 0.0001
 survivors 197.49
(117–326)
213.43
(129–337)
199.73
(110–343)
226.06
(129–335)
228.09
(134–368)
116.11
(117–326)
 non-survivors 165
(98–249)
309
(105–389)
279.5
(183–529)
629.01
(256–759)
619.10
(301–689)
503.50
(281–697)
 P 0.51 0.64 0.22 0.001 0.001 0.001
UNGAL values
  Pre-op. (97) Intra-op. (84) 6 h (87) 18 h (75) 24 h (71) 48 h (62)
 no AKI / mild AKI 27
(17–244)
35
(16–402)
40
(18–143)
62
(32–380)
72
(26–248)
147
(44–338)
 severe AKI 90
(23–254)
119
(26–1669)
424
(51–2802)
312
(55–1542)
329
(85–1290)
247
(50–1820)
 P 0.90 0.008 < 0.0001 0.006 0.004 0.23
 no-RRT 27(16–167) 26(15–98) 70(27–160) 78(35–262) 110(28–318) 70(18–317)
 need RRT 179
(34–513)
602
(34–2912)
1361(603–2131) 855
(335–1979)
660
(195–3109)
667
(102–1650)
 P 0.001 < 0.0001 < 0.0001 < 0.0001 0.001 0.002
 survivors 33
(15–372)
47.10
(20–522)
113.10
(28–817)
131.20
(37–818)
147.80
(42–546)
214.80
(95–1608)
 non-survivors 220.40
(49–549)
181.71
(42–3046)
1235.70
(77–3806)
309.69
(138–3718)
332.71
(109–3861)
3291
(340–3950)
 P 0.02 0.11 0.005 0.06 0.09 0.0004
  1. Data are expressed as median and percentile (interquartile range 25–75) as the nonparametric distribution UNGAL. The Shapiro–Wilk normality test was performed. AKI: acute kidney injury; RRT: renal replacement therapy