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Table 2 Progression of PNGAL and UNGAL in AKI, max KDIGO stage, need for RRT and mortality groups

From: Early detection of acute kidney injury in the perioperative period of liver transplant with neutrophil gelatinase-associated lipocalin

PNGAL values

 

Pre-op. (100)

Intra-op. (95)

6 h (90)

18 h (87)

24 h (86)

48 h (74)

 no AKI / mild AKI

172

(102–331)

196

(117–310)

138

(93–282)

170

(117–252)

156

(113–243)

116

(89–221)

 severe AKI

185

(114–287)

232

(158–364)

265

(177–429)

326

(180–616)

356

(215–666)

369

(235–535)

 P

0.82

0.50

0.047

0.004

< 0.0001

< 0.0001

 no-RRT

166 (79–270)

192

(127–323)

183

(86–281)

168

(120–249)

173

(122–286)

134 (91–248)

 need RRT

204 (115–465)

318

(204–407)

341

(242–510)

459

(306–749)

608

(333–749)

481 (292–689)

 P

0.27

0.015

< 0.0001

< 0.0001

< 0.0001

< 0.0001

 survivors

197.49

(117–326)

213.43

(129–337)

199.73

(110–343)

226.06

(129–335)

228.09

(134–368)

116.11

(117–326)

 non-survivors

165

(98–249)

309

(105–389)

279.5

(183–529)

629.01

(256–759)

619.10

(301–689)

503.50

(281–697)

 P

0.51

0.64

0.22

0.001

0.001

0.001

UNGAL values

 

Pre-op. (97)

Intra-op. (84)

6 h (87)

18 h (75)

24 h (71)

48 h (62)

 no AKI / mild AKI

27

(17–244)

35

(16–402)

40

(18–143)

62

(32–380)

72

(26–248)

147

(44–338)

 severe AKI

90

(23–254)

119

(26–1669)

424

(51–2802)

312

(55–1542)

329

(85–1290)

247

(50–1820)

 P

0.90

0.008

< 0.0001

0.006

0.004

0.23

 no-RRT

27(16–167)

26(15–98)

70(27–160)

78(35–262)

110(28–318)

70(18–317)

 need RRT

179

(34–513)

602

(34–2912)

1361(603–2131)

855

(335–1979)

660

(195–3109)

667

(102–1650)

 P

0.001

< 0.0001

< 0.0001

< 0.0001

0.001

0.002

 survivors

33

(15–372)

47.10

(20–522)

113.10

(28–817)

131.20

(37–818)

147.80

(42–546)

214.80

(95–1608)

 non-survivors

220.40

(49–549)

181.71

(42–3046)

1235.70

(77–3806)

309.69

(138–3718)

332.71

(109–3861)

3291

(340–3950)

 P

0.02

0.11

0.005

0.06

0.09

0.0004

  1. Data are expressed as median and percentile (interquartile range 25–75) as the nonparametric distribution UNGAL. The Shapiro–Wilk normality test was performed. AKI: acute kidney injury; RRT: renal replacement therapy