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Table 2 Comparing the pathology reports of the index for-cause biopsy done 19-months post kidney transplant and a follow-up 6-month biopsy

From: A case report on lipofuscin deposition in a graft biopsy two years after kidney transplantation: an insignificant bystander or a pathogenic benefactor?

Index biopsy

6-month follow up biopsy

Gross description:5 cores, ¾ renal cortex, 76 glomeruli, 3 globally sclerosed, 11 arteries

Gross description: 3 cores, all cortex, 22 glomeruli, 3 globally sclerosed, 9 arteries

Banff lesion scores:a

• i1, t0, v0, ti1, i-IFTA1

• g2, ptc2, v0, C4d0, cg0, mm1

• ci1, ct1, ah2, cv3

Banff lesion scores:a

• i0–1, t0–1, v0, ti1, i-IFTA?, t0

• g2, ptc1–2, v0, C4d0, cg0–1, mm1

• ci1–2, ct1–2, ah1, cv1

Miscellaneous: lipofuscin deposition, polyoma virus immunostaining negative, immunofluorescence negative to non-specific

Indeterminate antibody level against the major-histocompatibility-complex class I-related chain A

Miscellaneous: lipofuscin deposition, immunofluorescence negative to non-specific

No donor specific antibody

  1. aClassification based on Haas et al. Am J Transplant. 2018;18 (2):293–307