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Table 1 Comparison of baseline characteristics between cancer and no cancer patients in both total and matched samples

From: Cancer patterns and association with mortality and renal outcomes in non-dialysis dependent chronic kidney disease: a matched cohort study

 

Total sample

 

Propensity matched sample

Variable

Total (2952)

Cancer (339)

No cancer (2613)

p-Value

Total (674)

Cancer (337)

No cancer (337)

p-Value

Age, years

67 (56–76)

71 (63–77)

67 (55–75)

< 0.001

71 (63–77)

71 (63–77)

71 (61–78)

0.79

Male

1834 (62.1%)

221 (65.2%)

1613 (61.7%)

0.22

434 (64.4%)

220 (65.3%)

214 (63.5%)

0.63

Caucasian

2837 (96.1%)

337 (99%)

2500 (95.67%)

0.001

670 (99.4%)

335 (99.4%)

335 (99.4%)

1.00

Smoking

1941 (65.8%)

228 (67.3%)

1713 (65.5%)

0.54

450 (66.8%)

227 (67.3%)

223 (66.2%)

0.74

Alcohol

1375 (46.5%)

144 (43%)

1231 (47%)

0.11

289 (42.9%)

144 (42.7%)

145 (43%)

0.94

BMIa, kg/m2

28 (24–32.6)

28.3 (24.7–32.7)

28 (24.6–32.6)

0.60

28 (24.8–31.6)

28.3 (24.7–32.8)

27.8 (24.8–31)

0.22

Systolic BP, mmHg

138 (124–153)

140 (126–156)

138 (124–152)

0.019

139 (126–155)

140 (126–156)

138 (125–152)

0.22

Diastolic BP, mmHg

75 (66–80)

74 (66–80)

75 (66–80)

0.58

74 (66–80)

74 (66–80)

75 (68–80)

0.41

Hypertension

2684 (90.9%)

295 (87%)

2389 (91.4%)

0.008

593 (87.9%)

295 (87.5%)

298 (88.4%)

0.72

DM

961 (37.6%)

108 (31.9%)

853 (32.6%)

0.77

215 (31.9%)

108 (32%)

107 (31.7%)

0.93

CVD

1269 (43%)

151 (44.5%)

1118 (42.8%)

0.54

298 (44.2%)

151 (44.8%)

147 (43.6%)

0.76

COPD

545 (18.5%)

44 (12.9%)

501 (23.7%)

0.006

87 (12.9%)

44 (13.1%)

43 (12.7%)

0.91

CLD

88 (2.9%)

7 (2.1%)

81 (3.1%)

0.29

13 (1.9%)

7 (2.1%)

6 (1.8%)

0.78

RAS blocker

1799 (61%)

162 (47.7%)

1637 (62.6%)

< 0.001

312 (46.3%)

162 (48.1%)

150 (44.5%)

0.35

Statin

1732 (58.7%)

194 (57.2%)

1538 (59%)

0.57

391 (58%)

194 (57.6%)

197 (58.5%)

0.82

ESA

379 (12.8%)

40 (11.8%)

339 (13%)

0.54

73 (10.8%)

40 (11.8%)

33 (9.8%)

0.39

HB, g/L

123 (112–135)

121 (109–131)

123 (112–135)

0.02

122 (112–133)

121 (110–131)

123 (113–134)

0.05

Albumin, g/L

43 (40–45)

43 (40–45)

43 (40–45)

0.30

43 (40–45)

43 (40–45)

43 (40–45)

0.50

ALP, Units/L

82 (66–104)

85.5 (68–107)

82 (65–103)

0.04

84 (67–107)

85.5 (68–107)

85.5 (69–108.5)

0.99

Calcium, mmol/L

2.3 (2.2–2.4)

2.32 (2.2–2.4)

2.30 (2.2–2.4)

0.17

2.31 (2.2–2.4)

2.32 (2.2–2.4)

2.30 (2.2–2.4)

0.55

Phosphate, mmol/L

1.12 (0.97–1.3)

1.10 (0.95–1.3)

1.12 (0.98–1.3)

0.35

1.11 (0.96–1.3)

1.10 (0.95–1.3)

1.12 (0.97–1.3)

0.49

uPCRa, g/mol

31.5 (13–104)

34.23 (13.2–87)

31.2 (13–107)

0.49

33.3 (13.1–90.7)

33.7 (13.1–85)

32.1 (13.5–94.7)

0.64

Creatinine, micromol/L

182 (135–256)

188 (141–262)

179 (135–254)

0.16

185 (138–262)

187 (141–261)

183 (135–263)

0.53

eGFR, mL/min/1.73m2

30 (19.7–42.5)

28.3 (18.3–39.3)

30 (19.8–43)

0.02

29.3 (18.3–40.5)

28.7 (18.5–39.4)

29.6 (18–40.9)

0.60

  1. a-BMI missing in 530/2952 of total sample and in 124/674 of matched sample. b-missing uPCR values in 292 patients of total sample and 75 patients of matched sample
  2. BMI-body mass index, BP-blood pressure, DM-diabetes mellitus, CVD- cardio vascular disease (includes at least one of the following- ischemic heart disease, myocardial infarction, congestive cardiac failure, cerebrovascular accident, and peripheral vascular disease), COPD-chronic obstructive pulmonary disease, CLD-chronic liver disease, RAS-renin-angiotensin system blocker, ESA-erythropoietin stimulating agents, HB-haemoglobin, ALP-alkaline phosphatase, uPCR-urine protein creatinine ratio, eGFR - estimated glomerular filtration rate calculated by CKD-EPI equation
  3. Continuous variables are expressed as median (interquartile range) and p-Value by Man-Whitney U test
  4. Categorical variables are expressed as number (%) and p-Value by Chi-Square test. Statistically significant p-values are displayed in bold (i.e. p < 0.05)