Glycemia affects glomerular filtration rate in people with type 2 diabetes

BMC Nephrology

Table 2 Regression models for aGFR, 1/SCR and aGFR-eGFR

Variable	Β	SE	P-value
A	Log aGFR (log ml/min/1.73m²)
Intercept	5.8502	0.0430
Sex (female vs male)	−0.2151	0.0128	< 0.0001
Age (yrs)	−0.0100	0.0005	< 0.0001
Serum creatinine (mg/dl)	−0.8639	0.0334	< 0.0001
Fasting plasma glucose (10 mg/dl)	0.0061	0.0008	< 0.0001
HbA1c (%)	0.0061	0.0030	0.0402
B	1/SCR (dl/mg)
Intercept	1.4931	0.0566
Sex (female vs male)	0.2821	0.0218	< 0.0001
Age (yrs)	−0.0082	0.0009	< 0.0001
HbA1c (%)	0.0287	0.0033	< 0.0001
Fasting plasma glucose (10 mg/dl)	−0.0043	0.0007	< 0.0001
C	aGFR-eGFR (ml/min/1.73m²)
Intercept	39.7124	5.3606
Sex (female vs male)	−10.5330	1.5884	< 0.0001
Age (yrs)	−0.5928	0.0708	< 0.0001
Serum creatinine (mg/dl)	−11.2485	4.1942	0.0074
Fasting plasma glucose (10 mg/dl)	0.7927	0.0976	< 0.0001
HbA1c (%)	1.0216	0.3789	0.0071
Duration of diabetes	0.1916	0.08687	0.0275

Beta is the regression coefficient and SE is its standard error. Regression models were fit using a mixed model procedure to account for multiple examinations within individuals. Results are shown for best fitting model (lowest AIC)

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