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Table 3 IDO1 activity in hemodialyzed patients at the end of each trial treatment period

From: Vitamin e-loaded membrane dialyzers reduce hemodialysis inflammaging

 

BHD

VIT − E

HDF

Kyn, μmol/l

8.23 ± 1.57*

4.60 ± 1.63

6.81 ± 1.74*

L − Trp, μmol/l

17.90 ± 5.62

19.50 ± 5.42

17.22 ± 4.06

Kyn/Trp

45.81 ± 8.47*

23.58 ± 4.97

39.48 ± 6.13*

  1. IDO1, indoleamine 2,3-dioxygenase; BHD, standard low−flux bicarbonate hemodialysis with polysulfone membrane dialyzer; VIT − E, low−flux BHD with vitamin E − loaded polysulfone membrane (Excebrane®) dialyzer; HDF, hemodiafiltration with polysulfone membrane dialyzer; Kyn, kynurenine; L − Trp, l-tryptophan; Kyn/Trp, Kyn/ l-Trp ratio; data are M ± SD; *, P < 0.05 vs VIT − E
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BMC Nephrology

ISSN: 1471-2369

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