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Table 4 A comparison of outcomes between patients with a history of stroke at dialysis commencement compared with those without

From: Impact of prior stroke on major clinical outcome in chronic kidney disease: the Salford kidney cohort study

 

Stroke at dialysis commencement

p-value (stroke at dialysis commencement v no stroke at dialysis commencement)

No

N = 531

Yes

N = 48

Characteristics at Dialysis Initiation

 Age

64 (51–74)

68 (56.5–73.5)

0.141

 Male Gender

344 (64.8%)

38 (79.2%)

0.044

 Living Alone

93 (17.5%)

8 (16.7%)

0.878

 Widowed

46 (8.7%)

6 (12.5%)

0.568

 Ethnic Group

  Caucasian

497 (93.6%)

46 (95.8%)

0.930

 Primary renal disease

  Renovascular Disease/Hypertension

106 (20.0%)

17 (35.4%)

0.012

  Diabetic kidney disease

132 (24.9%)

12 (25.0%)

0.983

  Glomerulonephritis/Vasculitis

104 (19.6%)

4 (8.3%)

0.055

  Pyelonephritis

30 (5.6%)

2 (4.2%)

0.667

  Autosomal dominant Polycystic Kidney Disease

65 (12.2%)

5 (10.4%)

0.710

  Other/Unknown

94 (17.7%)

8 (16.7%)

0.857

 Smoking History

351 (74.1%)

34 (75.6%)

0.826

 Diabetes

195 (36.7%)

20 (41.7%)

0.497

 Heart Failure

74 (13.9%)

7 (14.6%)

0.901

 Myocardial infarction

78 (14.7%)

8 (16.7%)

0.712

 Peripheral vascular disease

117 (22.0%)

8 (16.7%)

0.387

 Atrial fibrillation

59 (11.1%)

6 (12.5%)

0.028

 Haemodialysis as first dialysis modality

347 (65.3%)

32 (66.7%)

0.854

Outcomes

 Non-Fatal Stroke

23 (4.3%)

0

 

 Death from stroke

4 (2.9%)

0

 

 Non-Fatal Myocardial infarction

58 (10.9%)

4 (8.3%)

0.578

 Death from acute myocardial infarctiona

24 (17.6%)

4 (25%)

0.498

 Death from cardiovascular diseaseb

50 (36.8%)

6 (37.5%)

0.954

 Newly identified Atrial Fibrillationc

28 (5.9%)

1 (2.4%)

0.303

 Transplanted

157 (29.6%)

10 (20.8%)

0.198

 Time from dialysis to transplant (months)

23 (8–38)

28 (20–37)

0.336

 All-cause mortality

259 (48.8%)

31 (64.6%)

0.036

 Time from dialysis to death (months)

28 (12–52)

16 (6–39)

0.093

 Age at death (years)

74 (64–78)

72 (64–77)

0.648

 Months of follow up from dialysis initiationd

25 (10–47)

20 (9–38)

0.303

  1. Continuous variables expressed as median (interquartile range) and categorical variables presented as number (%). Between group comparisons made using chi square test for categorical variables (2 sided fishers exact test when observed outcomes < 5) and Mann-U Whitney for continuous variables. Note that cause of death data available for 152 deaths (25.6% of deaths in non-stroke group and 33.3% of deaths in prevalent stroke group, p = 0.925, % when in relation to death data is proportion of deaths in patients whom cause of death is known)
  2. ausing terms myocardial infarction, coronary artery occlusion, cardiac arrest due to coronary artery disease as cause of death
  3. busing terms stroke, CVA, myocardial infarction, ruptured aneurysm, mesenteric thrombosis, left ventricular failure, cardiac dysrhythmia
  4. c% as proportion of patients without previous atrial fibrillation
  5. dcensored at 2/3/18, death, transplant or move out of area
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BMC Nephrology

ISSN: 1471-2369

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