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Table 2 Continuous renal replacement therapy metrics

From: Flexitrate regional citrate anticoagulation in continuous venovenous hemodiafiltration: a retrospective analysis

Variables

Flexitrate

N = 37

tRCA

N = 23

Heparin

N = 20

P-Valuea

Hours of CRRT Per Session

70 (27, 90)

95 (40, 155)

88 (37, 146)

NS

Blood Flow Rate (ml/min)

150

150

150

NS

Post-filter Replacement rate (ml/hr)

741 (600, 1000)

900 (500, 1280)

1083 (589, 1443)

NS

Dialysate rate (ml/hr)

1000 (1000, 1500)

1400 (1000, 1500)

1500 (1212, 1952)

P < 0.001

PBP rate (ml/hr)

1496 (1373, 1504)

142 (118, 167)

144 (100, 225)

P < 0.001

Fluid removal rate (ml/hr)

170 ± 92

219 ± 107

186 ± 63

NS

Total effluent rate (ml/hr)

3399 ± 599

2429 ± 631

2781 ± 819

P < 0.001

CRRT Dose (ml/kg/hr)

33 ± 6

28 ± 7

30 ± 8

P = 0.01

Concurrent treatment with Heparin

5.4%

39.1%

N/A

P = 0.002

  1. Results presented as Mean ± SD or Median (25th, 75th percentile). tRCA, Traditional Regional Anticoagulation. CRRT, Continuous Renal Replacement Therapy
  2. aP-value calculated using ANOVA, Chi-Square, or Kruskal-Wallis tests as appropriate. No significant differences were found between the tRCA and Heparin protocols in post-hoc analysis