Table 4 Metabolic outcome during the first 5 years after transplantation. Data are shown as mean ± SD. KTA, kidney transplant alone; SPK, Simultaneous Pancreas Kidney transplantation; POY, postoperative year
Variable | Group | Postoperative year | P- value preop vs 5-POY | P-value; SPK vs KTA, 5-POY | |||
|---|---|---|---|---|---|---|---|
Preoperative | 1 | 3 | 5 | ||||
HbA1c, % | SPK | 7.8 ± 1.7 | 5.8 ± 1.2 | 5.5 ± 1.7 | 5.6 ± 0.9 | < 0.01 | < 0.01 |
KTA | 6.7 ± 0.9 | 6.4 ± 1.3 | 7.1 ± 2.1 | 7.8 ± 1.9 | < 0.01 | ||
Cholesterol, mmol/l | SPK | 5.3 ± 2.1 | 4.9 ± 1.1 | 4.6 ± 0.9 | 4.9 ± 0.8 | 0.07 | 0.99 |
KTA | 4.9 ± 1.6 | 5.3 ± 1.8 | 5.1 ± 1.2 | 5.0 ± 1.4 | 0.76 | ||
Triglyceride, mmol/l | SPK | 2.1 ± 1.2 | 1.6 ± 1.1 | 1.3 ± 1.0 | 1.4 ± 0.9 | < 0.01 | < 0.01 |
KTA | 2.6 ± 1.2 | 2.9 ± 1.7 | 2.2 ± 1.3 | 3.1 ± 1.5 | 0.08 | ||
LDL- cholesterol, mmol/l | SPK | 2.6 ± 1.4 | 2.7 ± 0.6 | 2.6 ± 1.1 | 2.5 ± 0.8 | 0.82 | 0.84 |
KTA | 2.8 ± 1.4 | 3.1 ± 1.2 | 2.8 ± 0.9 | 2.7 ± 0.8 | 0.84 | ||
HDL- cholesterol, mmol/l | SPK | 1.5 ± 0.6 | 1.4 ± 0.3 | 1.7 ± 0.5 | 1.6 ± 0.3 | 0.89 | 0.01 |
KTA | 1.2 ± 0.4 | 1.1 ± 0.5 | 1.2 ± 0.2 | 1.3 ± 0.3 | 0.67 | ||
Serum creatinine, μmol/l | SPK | 156 ± 21 | 127 ± 8 | 132 ± 10 | 135 ± 11 | 0.04 | 0.12 |
KTA | 210 ± 29 | 161 ± 15 | 178 ± 25 | 195 ± 37 | 0.09 | ||