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Table 1 Comparison of basic clinical information of patients

From: High-throughput sequencing analysis of intestinal flora changes in ESRD and CKD patients

 

CKD (N = 17)

CT(N = 47)

HD(N = 49)

PD(N = 53)

Total

F/χ2 value

p value

M:F

13:4

23:24

28:21

29:24

93:73

3.91

0.272

Age

57.29 ± 11.13

56.30 ± 10.67

59.53 ± 10.57

57.70 ± 8.52

57.80 ± 10.03

0.85

0.47

Weight (kg)

57.70 ± 13.97

62.49 ± 8.10

58.12 ± 11.63

59.73 ± 11.03

59.83 ± 10.88

1.58

0.197

BUN (mmol/L)

25.86 ± 7.80

4.63 ± 0.93

23.53 ± 7.21

18.63 ± 6.61

16.85 ± 10.00

100.37

< 0.001

Creatinine (umol/L)

1022.94 ± 349.12

67.38 ± 15.53

963.14 ± 286.98

864.09 ± 288.10

684.02 ± 464.44

133.86

< 0.001

UA (umol/L)

452.80 ± 82.88

318.39 ± 63.24

453.63 ± 88.20

431.17 ± 89.58

408.08 ± 99.28

26.99

< 0.001

Albumin (g/L)

35.65 ± 4.05

42.13 ± 3.33

35.06 ± 4.67

32.97 ± 4.35

36.45 ± 5.54

43.55

< 0.001

Hb (g/L)

110.12 ± 14.10

136.72 ± 11.53

105.84 ± 16.59

101.11 ± 24.59

113.51 ± 23.42

36.59

< 0.001

WBC (10^9/L)

7.00 ± 1.96

6.27 ± 1.38

7.35 ± 2.83

7.12 ± 2.99

6.94 ± 2.50

1.67

0.18

CRP

5.29 ± 2.67

2.21 ± 0.99

5.13 ± 2.67

10.26 ± 21.04

5.96 ± 12.36

3.86

0.01

IL-6

6.68 ± 2.98

2.90 ± 2.52

6.61 ± 3.32

12.63 ± 15.30

7.49 ± 9.71

10.02

< 0.001

FBG

4.93 ± 0.66

5.19 ± 0.79

5.13 ± 0.67

5.70 ± 3.13

5.31 ± 1.87

1.24

0.29

HbAc

5.27 ± 0.51

4.91 ± 0.51

5.38 ± 0.66

5.30 ± 0.94

5.21 ± 0.73

3.98

0.009

TC

4.26 ± 4.05

4.85 ± 0.67

4.35 ± 1.00

5.10 ± 1.16

4.72 ± 1.02

6.69

< 0.001

Dialyze number (3/4/5)

–

–

–

5/45/3

 

–

–

Dialysis vintage (month)

–

–

35.35 ± 32.33

39.85 ± 39.44

 

0.63

0.532

Primary disease

 Chronic nephritis

4 (23.5)

–

16 (32.7)

21 (39.6)

 

23.792

0.002

 Hypertensive nephropathy

10 (58.8)

–

27 (55.1)

22 (41.5)

 

 Others

3 (17.6)

–

6 (12.2)

10 (18.9)

 

NYHA classification

 I

  

20 (40.8)

24 (45.3)

 

4.291

0.117

 II

  

17 (34.7)

24 (45.3)

   

 III

  

12 (24.5)

5 (9.4)

   

 Coronary disease

     

1.051

0.305

 Yes

  

29 (59.2)

26 (49.1)

   

 No

  

20 (40.8)

27 (50.9)

   

 Hypertension

     

0.962

0.327

 Yes

  

35 (71.4)

33 (62.3)

   

 No

  

14 (28.6)

20 (37.7)

   
  1. (CKD: chronic kidney disease; CT: control; HD: hemodialysis; PD: peritoneal dialysis; M: male; F: female; BUN: Blood Urea Nitrogen: UA: Uric Acid: Hb: Hemoglobin: WBC: White Blood Ccll: CRP: C-reactive protein: IL-6: Interleukin-6: FBG: Fasting Blood Glucose: HbAc: Glycated hemoglobin: TC: Total cholesterol)