Table 2 Baseline clinical and serologic characteristics
Parameter | no AKI | AKI-1 | AKI-2 | AKI-3 | P |
|---|---|---|---|---|---|
n(%) | 82 (49) | 40 (24) | 26 (16) | 19 (11) | |
Age (yr,mean ± SD) | 29 ± 9 | 30 ± 10 | 32 ± 12 | 30 ± 12 | 0.44 |
Female(n[%]) | 76 (93) | 39 (98) | 23 (89) | 17 (90) | 0.49 |
systolic BP (mmHg;mean ± SD) | 132 ± 23 | 141 ± 22 | 139 ± 24 | 150 ± 28 | 0.02 |
diastolic BP (mmHg;mean ± SD) | 86 ± 16 | 91 ± 15 | 88 ± 16 | 98 ± 14 | 0.01 |
Scr (mg/dl;mean ± SD) | 0.8 ± 0.1 | 1.4 ± 0.1 | 2.1 ± 0.4 | 5.9 ± 5.0 | < 0.01 |
Serum Alb(g/dl;mean ± SD) | 2.7 ± 0.7 | 2.5 ± 0.6 | 2.4 ± 0.6 | 2.3 ± 0.5 | 0.01 |
Hb(g/dl;mean ± SD) | 10.2 ± 2.1 | 9.6 ± 2.1 | 8.8 ± 2.1 | 7.4 ± 1.7 | < 0.01 |
Anti-dsDNA Ab positivity(n[%]) | 64 (78) | 29 (73) | 21 (81) | 15 (79) | 0.86 |
nephrotic syndrome(n[%]) | 55 (67) | 33 (83) | 23 (89) | 17 (90) | 0.03 |
C3(mg/dl;mean ± SD) | 0.4 ± 0.2 | 0.4 ± 0.2 | 0.3 ± 0.2 | 0.4 ± 0.1 | 0.76 |
Proteinuria(g/d;mean ± SD) | 3.7 ± 2.3 | 4.8 ± 3.0 | 4.5 ± 2.8 | 5.7 ± 4.7 | 0.03 |
eGFR (ml/min;mean ± SD) | 92 ± 23 | 49 ± 6 | 32 ± 7 | 17 ± 18 | < 0.01 |
MP pulse,(n[%]) | 20 (24) | 16 (40) | 16 (62) | 13 (68) | < 0.01 |
MMF,(n[%]) | 34 (42) | 15 (38) | 11 (42) | 6 (32) | 0.85 |
CTX,(n[%]) | 58 (73) | 26 (65) | 20 (77) | 11 (68) | 0.47 |