Table 2 Trajectory of key variables in the overall sample
Variables | Baseline | Month 3 | Month 6 | Month 9 | Month 12 | p-value |
|---|---|---|---|---|---|---|
Creatinine | 41.7 (3.7) | 41.5 (3.9) | 47.7 (4.1) | 52.1 (4.5) | 59.1 (5.0) | 0.0001 |
eGFR | 27.0 (2.3) | 30.3 (2.4) | 27.7 (2.5) | 27.0 (2.8) | 21.5 (3.1) | 0.003 |
Urea | 1.00 (0.08) | 0.97 (0.08) | 1.04 (0.09) | 1.01 (0.10) | 1.21 (0.11) | 0.178 |
SBP | 154.4 (3.2) | 142.1 (3.7) | 147.3 (3.9) | 145.5 (4.4) | 156.0 (5.1) | < 0.0001 |
DBP | 92.4 (2.0) | 85.4 (2.3) | 86.3 (2.4) | 83.9 (2.7) | 85.6 (3.1) | < 0.0001 |
Sodium | 136.9 (1.2) | 136.9 (1.5) | 136.1 (1.7) | 139.7 (2.0) | 140.4 (2.4) | 0.345 |
Potassium | 4.59 (0.12) | 4.55 (0.13) | 4.43 (0.14) | 4.67 (0.16) | 4.67 (0.20) | 0.382 |
Calcium | 87.4 (1.5) | 84.6 (2.2) | 88.1 (1.9) | 89.0 (2.6) | 88.0 (2.8) | 0.558 |
Haemoglobin | 10.2 (0.6) | 10.0 (0.7) | 9.6 (0.7) | 10.1 (0.8) | 11.1 (0.9) | 0.090 |
TCMH | 30.2 (1.4) | 30.4 (1.6) | 32.2 (1.7) | 31.4 (1.9) | 32.0 (2.7) | 0.535 |
VGM | 82.1 (2.1) | 78.8 (2.7) | 85.9 (2.9) | 84.9 (3.4) | 91.0 (4.5) | 0.051 |
Phosphate | 45.4 (3.0) | 40.7 (5.3) | 41.9 (4.0) | 45.9 (5.5) | 40.4 (5.3) | 0.624 |
Uric acid | 78.3 (3.9) | 67.6 (5.4) | 70.1 (5.1) | 68.3 (7.2) | 65.4 (8.2) | 0.034 |
Albumin | 30.5 (2.4) | 35.3 (3.0) | 27.8 (3.3) | 30.5 (4.1) | 37.0 (7.3) | 0.125 |
Total cholesterol | 2.4 (0.2) | 2.0 (0.2) | 1.8 (0.3) | 1.9 (0.3) | 2.6 (0.4) | 0.036 |
HDL cholesterol | 0.51 (0.06) | 0.36 (0.19) | 0.30 (0.15) | 0.44 (0.27) | 0.53 (0.24) | 0.685 |
Triglycerides | 1.7 (0.2) | 1.3 (0.4) | 1.6 (0.3) | 1.5 (0.4) | 1.4 (0.4 | 0.648 |